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Anuradha Chougule
Researcher at Tata Memorial Hospital
Publications - 59
Citations - 1044
Anuradha Chougule is an academic researcher from Tata Memorial Hospital. The author has contributed to research in topics: Lung cancer & Medicine. The author has an hindex of 14, co-authored 48 publications receiving 713 citations. Previous affiliations of Anuradha Chougule include Homi Bhabha National Institute.
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Gefitinib Versus Gefitinib Plus Pemetrexed and Carboplatin Chemotherapy in EGFR-Mutated Lung Cancer
Vanita Noronha,Vijay Patil,Amit Joshi,Nandini Menon,Anuradha Chougule,Abhishek Mahajan,Amit Janu,Nilendu Purandare,Rajesh Kumar,Sucheta More,Supriya Goud,Nandkumar Kadam,Nilesh Daware,Atanu Bhattacharjee,Srushti Shah,Akanksha Yadav,Vaishakhi Trivedi,Vichitra Behel,Amit Dutt,Shripad Banavali,Kumar Prabhash +20 more
TL;DR: Adding pemetrexed and carboplatin chemotherapy to gefitinib significantly prolonged PFS and OS but increased toxicity in patients with NSCLC.
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Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study
Eddy Pasquier,Eddy Pasquier,Nicolas André,Janine Street,Anuradha Chougule,Bharat Rekhi,Jaya Ghosh,Deepa Philip,Marie Meurer,Karen L. MacKenzie,Maria Kavallaris,Maria Kavallaris,Shripad Banavali +12 more
TL;DR: The results provide a strong rationale for the combination of β-blockers and vinblastine-based metronomic chemotherapy for the treatment of advanced angiosarcoma and highlights the potential of drug repositioning in combination with metronome chemotherapy in low- and middle-income country setting.
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Actionable Activating Oncogenic ERBB2/HER2 Transmembrane and Juxtamembrane Domain Mutations
Kanika Bajaj Pahuja,Thong T. Nguyen,Bijay S. Jaiswal,Kumar Prabhash,Tarjani M. Thaker,Kate Senger,Subhra Chaudhuri,Noelyn M. Kljavin,Aju Antony,Sameer Phalke,Prasanna Kumar,Marco Mravic,Eric Stawiski,Derek Vargas,Steffen Durinck,Ravi Gupta,Arati Khanna-Gupta,Sally E. Trabucco,Ethan Sokol,Ryan J. Hartmaier,Ashish Singh,Anuradha Chougule,Vaishakhi Trivedi,Amit Dutt,Vijay Patil,Amit Joshi,Vanita Noronha,James Ziai,S D Banavali,Vedam L. Ramprasad,William F. DeGrado,Raphael Bueno,Natalia Jura,Somasekar Seshagiri +33 more
TL;DR: Structural modeling and analysis showed that the TMD/JMD mutations function by improving the active dimer interface or stabilizing an activating conformation, and it was found that HER2 G660D employed asymmetric kinase dimerization for activation and signaling.
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Frequency of EGFR Mutations in 907 Lung Adenocarcioma Patients of Indian Ethnicity
Anuradha Chougule,Kumar Prabhash,Vanita Noronha,Amit Joshi,Abhishek Thavamani,Pratik Chandrani,Pawan Upadhyay,Sagarika Utture,Saral Desai,Nirmala A. Jambhekar,Amit Dutt +10 more
TL;DR: The intermediate frequency of EGFR mutation among Indian population compared to Caucasians and East Asians is reminiscent of an ancestral admixture of genetic influence from Middle Easterners, Central Asians, and Europeans on modern- Indian population that may confer differential susceptibility to somatic mutations in EGFR.
Journal Article
Haematologic and immunophenotypic profile of acute myeloid leukemia: An experience of Tata Memorial Hospital
S Ghosh,SC Shinde,G S Kumaran,R.S. Sapre,Subodh Dhond,Y Badrinath,Rashida Ansari,Ashok Kumar,Shashikant Mahadik,Anuradha Chougule,Nair Cn +10 more
TL;DR: A retrospective analysis of 260 cases of AML diagnosed at this institution between 1998 and 2000 found myeloperoxidase stain was a useful tool in the diagnosis of myeloid leukemias.