Aránzazu del Campo

TL;DR: This review highlights the challenge of photoactivation in vivo, and presents strategies for light management that can be adopted for this purpose, and focuses on technologies that are materials‐driven, particularly upconversion nanoparticles that assist in “direct path’ light delivery through tissue, and optical waveguides that “clear the path” between external light source and in vivo target.

TL;DR: It is believed the QCM-D strategy can be extended to other photoactivatable ligands to characterize cell membrane receptors activity, a relevant issue for cancer diagnosis (and prognosis) as well as other several pathologies.

TL;DR: The thiol-methylsulfone reaction is introduced as alternative crosslinking chemistry for cell encapsulation, particularized for PEG-hydrogels, and 3D cell culture of two cell types, fibroblasts and human umbilical vein endothelial cells (HUVECs), is demonstrated.

TL;DR: In this article, a review of recently developed polymers bearing reversible or irreversible photosensitive chromophores is presented, which can be remotely controlled by light, leading to a wide range of applications such as controlled drug delivery, micropattern, responsive hydrogel, degradable materials, and soft actuators.

TL;DR: It is shown that migration can be manipulated by flat stiffness patterns, although surface undulations also play a strong role, and speed to play little role in the migration efficiency and to be mainly influenced by the top layer modulus.