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Argyris Papantonis
Researcher at University of Göttingen
Publications - 107
Citations - 3511
Argyris Papantonis is an academic researcher from University of Göttingen. The author has contributed to research in topics: Chromatin & Gene. The author has an hindex of 26, co-authored 91 publications receiving 2535 citations. Previous affiliations of Argyris Papantonis include National and Kapodistrian University of Athens & University of Oxford.
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Journal ArticleDOI
Exon Skipping Is Correlated with Exon Circularization.
TL;DR: It is found that circularization of exons is widespread and correlates with exon skipping, a feature that adds considerably to the regulatory complexity of the human transcriptome.
Journal ArticleDOI
Nonspecific bridging-induced attraction drives clustering of DNA-binding proteins and genome organization.
Chris A. Brackley,Stephen S. Taylor,Argyris Papantonis,Argyris Papantonis,Peter R. Cook,Davide Marenduzzo +5 more
TL;DR: Molecular dynamics simulations are used to simulate reversible binding of proteins to DNA and uncover an unexpected force driving DNA compaction and protein aggregation that is driven by an entropic bridging-induced attraction that minimizes bending and looping penalties in the template.
Journal ArticleDOI
Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids
Elke Gabriel,Anand Ramani,Ulrike Karow,Marco Gottardo,Karthick Natarajan,Li Ming Gooi,Gladiola Goranci-Buzhala,Oleg Krut,Franziska Peters,Milos Nikolic,Suvi Kuivanen,Essi M. Korhonen,Teemu Smura,Olli Vapalahti,Argyris Papantonis,Jonas Schmidt-Chanasit,Maria Giovanna Riparbelli,Giuliano Callaini,Martin Krönke,Olaf Utermöhlen,Jay Gopalakrishnan +20 more
TL;DR: Two recently isolated strains of ZIKV, an American strain from an infected fetal brain and a closely-related Asian strain, productively infect human iPSC-derived brain organoids, showing the structural changes seen after infection closely resemble those seen in ZikV-associated microcephaly.
Journal ArticleDOI
Transcription factories: genome organization and gene regulation.
Argyris Papantonis,Peter R. Cook +1 more
TL;DR: It is argued that transcription 'factories' are central organizers of the human genome during interphase, and that proximity to an appropriate factory determines the activity of a gene.
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Enhancers and silencers: an integrated and simple model for their function
TL;DR: Regulatory DNA elements such as enhancers, silencers and insulators are embedded in metazoan genomes, and they control gene expression during development and a parsimonious model for their function is proposed.