Armelle Hebert

TL;DR: The approach allowed us to define the EDBPs that it is most important to monitor in order to assess population exposure and related public health issues, and thus to improve drinking water treatment and distribution.

TL;DR: Some of the wastewater and surface water samples were found to exceed the effect-based trigger values for estrogenic and glucocorticoid activity, suggesting these environmental waters may pose a potential risk to ecosystem health, while the lack of bioassay activity and low detected chemical concentrations in the drinking water samples do not suggest a risk to human endocrine health.

TL;DR: Assessing whether current in vitro bioassays are suitable to detect endocrine activity in a range of water types can help provide guidance on in vitroBioassay selection and required sample enrichment for optimised detection of endocrineactivity in environmental waters.

TL;DR: In this paper, the bioanalytical equivalent concentration (BEQ) approach was applied for the first time to determine the contribution of DBPs, with DBPs found to contribute between 17 and 58% of the oxidative stress response.

TL;DR: The whole animal Xenopus Embryonic Thyroid Assay (XETA) detected some activity in the unspiked surface water and treated wastewater extracts, but not in unspiking drinking water, and appears to be a suitable assay to detect thyroid activity in environmental waters.