A
Arthur I. Skoultchi
Researcher at Albert Einstein College of Medicine
Publications - 136
Citations - 13641
Arthur I. Skoultchi is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Chromatin & Histone H1. The author has an hindex of 55, co-authored 134 publications receiving 12349 citations. Previous affiliations of Arthur I. Skoultchi include Yeshiva University.
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Journal ArticleDOI
Drosophila linker histone H1 coordinates STAT-dependent organization of heterochromatin and suppresses tumorigenesis caused by hyperactive JAK-STAT signaling.
TL;DR: It is shown here that STAT92E is a second partner of H1 in the regulation of heterochromatin structure, enabling H1 to act as a tumor suppressor and oppose an oncogenic mutation in the JAK-STAT signaling pathway.
Journal Article
A comparative encyclopedia of DNA elements in the mouse genome" Nature
Feng Yue,Yong Cheng,Alessandra Breschi,Jeff Vierstra,Weisheng Wu,Tyrone Ryba,Richard Sandstrom,Zhihai Ma,Carrie A. Davis,Benjamin D. Pope,Yin Shen,Dmitri D. Pervouchine,Sarah Djebali,Robert Thurman,Rajinder Kaul,Eric Rynes,Anthony Kirilusha,Georgi K. Marinov,Brian A. Williams,Diane Trout,Henry Amrhein,Katherine I. Fisher-Aylor,Igor Antoshechkin,Gilberto DeSalvo,Lei-Hoon See,Megan Fastuca,Jorg Drenkow,Chris Zaleski,Alexander Dobin,Pablo Prieto,Julien Lagarde,Giovanni Bussotti,Andrea Tanzer,Olgert Denas,Kanwei Li,Michaël Bender,Miaohua Zhang,Rachel Byron,Mark Groudine,David F. McCleary,Long Pham,Zhen Ye,Samantha Kuan,Lee Edsall,Yi-Chieh Wu,Marie-Louise Hee Rasmussen,Mukul S. Bansal,Manolis Kellis,Cheryl A. Keller,Christopher T. Morrissey,Tejaswini Mishra,Deepti Jain,Nergiz Dogan,Raymond C. Harris,Philip Cayting,Trupti Kawli,Alan P. Boyle,Ghia Euskirchen,Anshul Kundaje,Shin Lin,Yiing Lin,Camden Jansen,Venkat S. Malladi,Melissa S. Cline,Drew T. Erickson,Vanessa M. Kirkup,Katrina Learned,Cricket A. Sloan,Kate R. Rosenbloom,d.B. Lacerda,Kathryn Beal,Miguel Pignatelli,Paul Flicek,Jin Lian,Tamer Kahveci,Dongwon Lee,W. J. Kent,S.M. Ramalho,Javier Herrero,Cedric Notredame,Andrew D. Johnson,Shinny Vong,Kristen Lee,Daniel Bates,Fidencio J. Neri,Morgan Diegel,T. Canfield,Peter J. Sabo,Matthew S. Wilken,Thomas A. Reh,Erika Giste,Anthony Shafer,Tanya Kutyavin,Eric Haugen,Douglas Dunn,Shane Neph,Richard Humbert,Robin L Hansen,M.H.L. de Bruijn,Licia Selleri,Alexander Y. Rudensky,Steven Z. Josefowicz,Robert M. Samstein,Evan E. Eichler,Stuart H. Orkin,Dana N. Levasseur,Thalia Papayannopoulou,Kai-Hsin Chang,Arthur I. Skoultchi,Srikanta Gosh,Christine M. Disteche,Piper R. Treuting,Yanli Wang,Mitchell G. Weiss,Gerd A. Blobel,Xiaoyi Cao,Sheng Zhong,Ting Wang,Peter Good,Rebecca F. Lowdon,Leslie B Adams,X. Zhou,Michael J. Pazin,Elise A. Feingold,Barbara J. Wold,Jeremy F. Taylor,Ali Mortazavi,Sherman M. Weissman,John A. Stamatoyannopoulos,Michael Snyder,Roderic Guigó,Thomas R. Gingeras,David M. Gilbert,Ross C. Hardison,Michael A. Beer,Bing Ren +135 more
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Expression of mouse histone genes: transcription into 3' intergenic DNA and cryptic processing sites downstream from the 3' end of the H3 gene
TL;DR: Results indicate that transcription may normally proceed a substantial distance past the hairpin loop, as judged by the extent of transcription of downstream sequences in isolated nuclei in the endogenous histone H3.1 gene.
Journal ArticleDOI
Cotransfer of circular and linear prokaryotic and eukaryotic DNA sequences into mouse cells
Nancy Hsiung,Hans M. Warrick,J. K. Deriel,Dorothy Tuan,Forget Bg,Arthur I. Skoultchi,Raju Kucherlapati +6 more
TL;DR: The authors have attempted to introduce some eukaryotic and prokaryotic DNA sequences into mouse fibroblasts and were unable to detect any transcripts of the human beta-globin gene at a level greater than or equal to 10 molecules per cell.
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Regulated expression of a chimeric histone gene introduced into mouse fibroblasts.
TL;DR: Chimeric mRNA levels were regulated in parallel with endogenous H3 mRNAs, suggesting that cis-acting regulatory sequences lie within or near individual histone genes.