Secret History: Return of the Black Death Channel 4, 7-8pm In 1348 the Black Death swept through London, killing people within days of the appearance of their first symptoms. Exactly how many died, and why, has long been a mystery. This Secret History documentary follows experts as they pick through the evidence and reveal why the plague killed on such a scale. And they ask, what might be coming next?

Medscape

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/pdf/acc-aha-2005-guideline-update-for-the-diagnosis-and-4hik65ngbe.pdf

ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult

In 1974 an article appeared in Science magazine with the dry-sounding title “Judgment Under Uncertainty: Heuristics and Biases” by a pair of psychologists who were not well known outside their discipline of decision theory. In it Amos Tversky and Daniel Kahneman introduced the world to Prospect Theory, which mapped out how humans actually behave when faced with decisions about gains and losses, in contrast to how economists assumed that people behave. Prospect Theory turned Economics on its head by demonstrating through a series of ingenious experiments that people are much more concerned with losses than they are with gains, and that framing a choice from one perspective or the other will result in decisions that are exactly the opposite of each other, even if the outcomes are monetarily the same. Prospect Theory led cognitive psychology in a new direction that began to uncover other human biases in thinking that are probably not learned but are part of our brain’s wiring.

Thinking fast and slow.

ACC/AHA 2005 guideline update for the diagnosis and management of chronic heart failure in the adult: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Update the 2001 Guidelines for the Evaluation and Management of Heart Failure).

Mariell Jessup, MD, FACC, FAHA, Chair [*][1]

William T. Abraham, MD, FACC, FAHA[†][2]

Donald E. Casey, MD, MPH, MBA[‡][3]

Arthur M. Feldman, MD, PhD, FACC, FAHA[§][4]

Gary S. Francis, MD, FACC, FAHA[§][4]

Theodore G. Ganiats, MD[∥][5]

Marvin A. Konstam, MD, FACC[¶][6]

Donna M.

/pdf/2009-focused-update-incorporated-into-the-acc-aha-2005-3z9lhvyqwq.pdf

2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in Collaboration With the International Society for Heart and Lung Transplantation

Ensuring the future of uterine transplantation.

http://www.thelancet.com/article/S0140673622008753/pdf

Effectiveness of vaccination mandates in improving uptake of COVID-19 vaccines in the USA

Introduction-Beyond Babies Doe- The Child, Medicine, and Science- Caring for Babies in Danger: The Evolution and Current State of Neonatology- Science and Controversy in the History of Infancy in America- Response to "Science and Controversy in the History of Infancy in America"- Which Babies Shall Live?-Comment on "Science and Controversy in the History of Infancy in America"- Religion, Suffering, and Morality- Our Religious Traditions and the Treatment of Infants- "Suffer the Little Children " Suffering and Neonatal Intensive Care- Ethical Principles for the Care of Imperiled Newborns: Toward an Ethic of Ambiguity- The Right to Privacy as a Protection for the Right to Refuse Care for the Imperiled Newborn- Images of the Abandoned- The Tyranny of the Normal- Comment on "The Tyranny of the Normal"- Caretakers: Images and Attitudes- Consensus and Controversy in the Treatment of Catastrophically Ill Newborns: Report of a Survey- Conclusion

Which Babies Shall Live?: Humanistic Dimensions of the Care of Imperiled Newborns

Institutional review boards (IRBs) have become beleaguered by a growth in responsibilities related to research oversight in the past several decades A number of regulatory bodies have appeared in response to these novel and complex responsibilities, seeking to respond to among other issues, conflicts of interest, new technologies, and the potential misuse of research findings Here, we examine several examples of these novel regulatory bodies as well as a number of concerns related to them that have been largely unacknowledged Evidence suggests that there can be disharmony and conflicts between these regulatory bodies and IRBs, a lack of clarity with regard to their roles and responsibilities, as well as shortcomings within these entities that, at times, look a lot like the worries that have long been raised in relation to IRBs We offer a brief discussion of how some of these concerns might be ameliorated, either through a significant restructuring of the system of research oversight, or perhaps through smaller changes to these regulatory bodies

Of Straws, Camels, Research Regulation, and IRBs:

Recent disputes concerning the development and application of new knowledge and new therapies in the biomedical sciences have created a new industry of sorts — bioethics. This is not to say that advances in medical science prior to the 1960’s and 1970’s moved ahead with little attention to moral concerns. Nor is it to say that biomedical research and therapy prior to the 1960’s was conducted in an immoral or amoral manner. Rather, as new advances in biomedicine enabled physicians to intervene with greater power in the lives of their patients, many in the health professions and the humanities found themselves increasingly concerned about the normative issues raised by the administration of new technologies to preserve or maintain the lives of the very young, the very old and the very ill.

Arthur L. Caplan

Papers

Ensuring the future of uterine transplantation.

Effectiveness of vaccination mandates in improving uptake of COVID-19 vaccines in the USA

Which Babies Shall Live?: Humanistic Dimensions of the Care of Imperiled Newborns

Of Straws, Camels, Research Regulation, and IRBs:

Applying Morality to Advances in Biomedicine: Can and should this be Done?