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Atsuyuki Igarashi
Researcher at NTT Medical Center
Publications - 76
Citations - 3636
Atsuyuki Igarashi is an academic researcher from NTT Medical Center. The author has contributed to research in topics: Psoriasis & Psoriasis Area and Severity Index. The author has an hindex of 24, co-authored 67 publications receiving 2911 citations. Previous affiliations of Atsuyuki Igarashi include Nippon Telegraph and Telephone & University of Tokyo.
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Journal ArticleDOI
Role and interaction of connective tissue growth factor with transforming growth factor-beta in persistent fibrosis: A mouse fibrosis model.
Toshifumi Mori,Shigeru Kawara,Mikio Shinozaki,Nobukazu Hayashi,Takashi Kakinuma,Atsuyuki Igarashi,Masaharu Takigawa,Toru Nakanishi,Kazuhiko Takehara +8 more
TL;DR: It appears that interaction of several growth factors is required for persistent fibrotic tissue formation, with TGF‐β causing the induction and CTGF needed for maintenance of skin fibrosis.
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Connective Tissue Growth Factor Gene Expression in Tissue Sections From Localized Scleroderma, Keloid, and Other Fibrotic Skin Disorders
Atsuyuki Igarashi,Kiyoko Nashiro,Kanako Kikuchi,Shinichi Sato,Hironobu Ihn,Manabu Fujimoto,Gary R. Grotendorst,Kazuhiko Takehara +7 more
TL;DR: The findings reinforce a correlation between CTGF gene expression and skin sclerosis and support the hypothesis that transforming growth factor-beta plays an important role in the pathogenesis of fibrosis, as it is the only inducer for CTGF identified to date.
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Myositis-specific anti-155/140 autoantibodies target transcription intermediary factor 1 family proteins.
Manabu Fujimoto,Yasuhito Hamaguchi,Kenzo Kaji,Takashi Matsushita,Yuki Ichimura,Masanari Kodera,Naoko Ishiguro,Ikuko Ueda-Hayakawa,Yoshihide Asano,Fumihide Ogawa,Keita Fujikawa,Takuya Miyagi,Eriko Mabuchi,Kenji Hirose,Narihiro Akimoto,Naohito Hatta,Kiyohiro Tsutsui,Akira Higashi,Atsuyuki Igarashi,Mariko Seishima,Minoru Hasegawa,Kazuhiko Takehara +21 more
TL;DR: To identify the 140-kd autoantigen recognized by anti-155/140 autoantibodies that are associated with adult cancer-associated dermatomyositis and juvenile DM and to determine the clinical relevance of anti- 155/140 antibodies in a large cohort is determined.
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Anti-NXP2 autoantibodies in adult patients with idiopathic inflammatory myopathies: possible association with malignancy
Yuki Ichimura,Takashi Matsushita,Yasuhito Hamaguchi,Kenzo Kaji,Minoru Hasegawa,Yoshinori Tanino,Yayoi Inokoshi,Kazuhiro Kawai,Takuro Kanekura,Maria Habuchi,Atsuyuki Igarashi,Ryosuke Sogame,Takashi Hashimoto,Tomohiro Koga,Ayako Nishino,Naoko Ishiguro,N. Sugimoto,Rui Aoki,Noriko Ando,Testsuya Abe,Takashi Kanda,Masataka Kuwana,Kazuhiko Takehara,Manabu Fujimoto +23 more
TL;DR: While less common than in juvenile IIM, anti-NXP2 Ab was found inAdult IIM and may be associated with adult IIM with malignancy.
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Efficacy and safety of ustekinumab in Japanese patients with moderate-to-severe plaque-type psoriasis: Long-term results from a phase 2/3 clinical trial
TL;DR: Ustekinumab was efficacious and generally well‐tolerated in Japanese patients with moderate‐to‐severe plaque‐type psoriasis through 72 weeks, consistent with those reported in the global, phase 3 studies.