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Aurélie Cobat
Researcher at French Institute of Health and Medical Research
Publications - 126
Citations - 9607
Aurélie Cobat is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 30, co-authored 101 publications receiving 6047 citations. Previous affiliations of Aurélie Cobat include McGill University Health Centre & Rockefeller University.
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Journal ArticleDOI
Genome-wide association study of resistance to Mycobacterium tuberculosis infection identifies a locus at 10q26.2 in three distinct populations.
Jocelyn Quistrebert,Jocelyn Quistrebert,Marianna Orlova,Marianna Orlova,Gaspard Kerner,Gaspard Kerner,Gaspard Kerner,Le Thi Ton,Nguyen Trong Luong,Nguyen Thanh Danh,Quentin B. Vincent,Quentin B. Vincent,Fabienne Jabot-Hanin,Fabienne Jabot-Hanin,Yoann Seeleuthner,Yoann Seeleuthner,Jacinta Bustamante,Jacinta Bustamante,Stéphanie Boisson-Dupuis,Nguyen Thu Huong,Nguyen Ngoc Ba,Jean-Laurent Casanova,Christophe Delacourt,Eileen G. Hoal,Alexandre Alcaïs,Alexandre Alcaïs,Vu Hong Thai,Laurent Abel,Laurent Abel,Laurent Abel,Erwin Schurr,Erwin Schurr,Aurélie Cobat,Aurélie Cobat +33 more
TL;DR: In this article, a genome-wide significant locus on chromosome 10q26.2 with a cluster of variants associated with strong protection against M. tuberculosis infection (OR = 0.42, 95%CI 0.35-0.55, P = 1.26×10-9).
Journal ArticleDOI
Prevalence and risk factors for latent tuberculosis infection among healthcare workers in Morocco.
Ayoub Sabri,Jocelyn Quistrebert,Jocelyn Quistrebert,Hicham Naji Amrani,Ahmed Abid,A. Zegmout,Ismail Abderrhamani Ghorfi,H. Souhi,A. Boucaid,Anas Benali,Rachid Abilkassem,M. Kmari,A. Hassani,Belyamani Lahcen,S. Siah,Erwin Schurr,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Jean-Laurent Casanova,Amine Lahlou,Abdelkader Laatiris,Lhoussain Louzi,Aziz Ouarssani,Ahmed Bourazza,Aziz Aouragh,Bensghir Mustapha,Nezha Messaoudi,Aomar Agader,Aurélie Cobat,Aurélie Cobat,Aurélie Cobat,Laurent Abel,Laurent Abel,Laurent Abel,Jamila El Baghdadi +35 more
TL;DR: Male gender, increased age, family history of TB, and working at a pulmonology unit were consistent risk factors associated with LTBI in HCWs living in Morocco.
Journal ArticleDOI
CUBN and NEBL common variants in the chromosome 10p13 linkage region are associated with multibacillary leprosy in Vietnam.
Audrey V. Grant,Audrey V. Grant,Aurélie Cobat,Aurélie Cobat,Nguyen Van Thuc,Marianna Orlova,Nguyen Thu Huong,Jean Gaschignard,Jean Gaschignard,Andrea Alter,Andrea Alter,Nguyen Ngoc Ba,Vu Hong Thai,Laurent Abel,Laurent Abel,Laurent Abel,Alexandre Alcaïs,Alexandre Alcaïs,Erwin Schurr,Erwin Schurr,Erwin Schurr +20 more
TL;DR: A new model for the genetic control of polarization of clinical leprosy is proposed using a high-density association mapping of the 9.5 Mb linkage peak on chromosome region 10p13 covering 39 genes.
Journal ArticleDOI
A new 3p25 locus is associated with liver fibrosis progression in human immunodeficiency virus/hepatitis C virus-coinfected patients
Damien Ulveling,Sigrid Le Clerc,Aurélie Cobat,Taoufik Labib,Josselin Noirel,Vincent Laville,Cédric Coulonges,Wassila Carpentier,Bertrand Nalpas,Markus H. Heim,Thierry Poynard,Andreas Cerny,Stanislas Pol,Pierre-Yves Bochud,François Dabis,Ioannis Theodorou,Yves Levy,Dominique Salmon,Laurent Abel,Stéphanie Dominguez,Jean-François Zagury +20 more
TL;DR: This genome‐wide association study identified a new locus associated with liver fibrosis severity in patients with HIV/HCV coinfection, on chromosome 3p25, a finding that was replicated in Patients with HCV monoinfection.
Journal ArticleDOI
Génétique humaine de la tuberculose
J. El Baghdadi,Audrey V. Grant,Audrey V. Grant,Ayoub Sabri,S El Azbaoui,H. Zaidi,Aurélie Cobat,Erwin Schurr,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Jean-Laurent Casanova,Laurent Abel,Laurent Abel,Laurent Abel +14 more
TL;DR: In this paper, a first major locus for pulmonary TB was mapped to chromosome 8q12-q13 in a Moroccan population after a genome-wide linkage screen using a similar strategy, two other major loci controlling TB infection were recently identified.