F
Fabienne Jabot-Hanin
Researcher at Paris Descartes University
Publications - 22
Citations - 1056
Fabienne Jabot-Hanin is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Gene & Medicine. The author has an hindex of 10, co-authored 15 publications receiving 748 citations. Previous affiliations of Fabienne Jabot-Hanin include French Institute of Health and Medical Research.
Papers
More filters
Journal ArticleDOI
Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
Satoshi Okada,Satoshi Okada,Janet Markle,Elissa K. Deenick,Elissa K. Deenick,Federico Mele,Dina Averbuch,M. Lagos,M. Lagos,Mohammed Alzahrani,Saleh Al-Muhsen,Rabih Halwani,Cindy S. Ma,Cindy S. Ma,Natalie Wong,Claire Soudais,Lauren A. Henderson,Hiyam Marzouqa,Jamal Shamma,Marcela Gonzalez,Rubén Martínez-Barricarte,Chizuru Okada,Danielle T. Avery,Daniela Latorre,Caroline Deswarte,Caroline Deswarte,Fabienne Jabot-Hanin,Fabienne Jabot-Hanin,Egídio Torrado,Jeffrey J. Fountain,Aziz Belkadi,Aziz Belkadi,Yuval Itan,Bertrand Boisson,Mélanie Migaud,Mélanie Migaud,Cecilia S. Lindestam Arlehamn,Alessandro Sette,Sylvain Breton,James McCluskey,Jamie Rossjohn,Jamie Rossjohn,Jamie Rossjohn,Jean-Pierre de Villartay,Despina Moshous,Sophie Hambleton,Sylvain Latour,Peter D. Arkwright,Capucine Picard,Olivier Lantz,Dan Engelhard,Masao Kobayashi,Laurent Abel,Laurent Abel,Laurent Abel,Andrea M. Cooper,Luigi D. Notarangelo,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Anne Puel,Anne Puel,Anne Puel,Federica Sallusto,Jacinta Bustamante,Stuart G. Tangye,Stuart G. Tangye,Jean-Laurent Casanova +67 more
TL;DR: People with loss-of-function mutations in the transcription factor RORC exhibit a surprising susceptibility to Mycobacterium, whereas inborn errors of interferon-γ (IFN-γ) immunity underlie mycobacterial disease.
Journal ArticleDOI
Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23
Rubén Martínez-Barricarte,Janet Markle,Cindy S. Ma,Elissa K. Deenick,Noé Ramírez-Alejo,Federico Mele,Daniela Latorre,Seyed Alireza Mahdaviani,Caner Aytekin,Davood Mansouri,Vanessa L. Bryant,Vanessa L. Bryant,Vanessa L. Bryant,Fabienne Jabot-Hanin,Caroline Deswarte,Caroline Deswarte,Alejandro Nieto-Patlán,Laura Surace,Gaspard Kerner,Gaspard Kerner,Yuval Itan,Yuval Itan,Sandra Jovic,Danielle T. Avery,Natalie Wong,Geetha Rao,Etienne Patin,Etienne Patin,Satoshi Okada,Benedetta Bigio,Bertrand Boisson,Bertrand Boisson,Bertrand Boisson,Franck Rapaport,Yoann Seeleuthner,Yoann Seeleuthner,Monika Schmidt,Aydan Ikinciogullari,Figen Dogu,Gönül Tanır,Payam Tabarsi,Mohammed Reza Bloursaz,Julia K. Joseph,Avneet Heer,Xiao-Fei Kong,Mélanie Migaud,Mélanie Migaud,Tomi Lazarov,Frederic Geissmann,Frederic Geissmann,Frederic Geissmann,Bernhard Fleckenstein,Cecilia S. Lindestam Arlehamn,Alessandro Sette,Alessandro Sette,Anne Puel,Anne Puel,Anne Puel,Jean-François Emile,Esther van de Vosse,Lluis Quintana-Murci,Lluis Quintana-Murci,James P. Di Santo,Laurent Abel,Laurent Abel,Laurent Abel,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Jacinta Bustamante,Stuart G. Tangye,Federica Sallusto,Jean-Laurent Casanova +72 more
TL;DR: These experiments of nature show that human IL-12 and IL-23 are both required for optimal IFN-γ–dependent immunity to mycobacteria, both individually and much more so cooperatively.
Journal ArticleDOI
Tuberculosis and impaired IL-23–dependent IFN-γ immunity in humans homozygous for a common TYK2 missense variant
Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Noé Ramírez-Alejo,Zhi Li,Zhi Li,Etienne Patin,Etienne Patin,Geetha Rao,Gaspard Kerner,Gaspard Kerner,Che Kang Lim,Che Kang Lim,Dimitry N. Krementsov,Nicholas Hernandez,Cindy S. Ma,Cindy S. Ma,Qian Zhang,Qian Zhang,Janet Markle,Rubén Martínez-Barricarte,Kathryn Payne,Robert Fisch,Caroline Deswarte,Caroline Deswarte,Joshua Halpern,Matthieu Bouaziz,Matthieu Bouaziz,Jeanette Mulwa,Durga Sivanesan,Durga Sivanesan,Tomi Lazarov,Rodrigo Naves,Patricia García,Yuval Itan,Yuval Itan,Bertrand Boisson,Bertrand Boisson,Bertrand Boisson,Alix Checchi,Alix Checchi,Fabienne Jabot-Hanin,Fabienne Jabot-Hanin,Aurélie Cobat,Aurélie Cobat,Andrea Guennoun,Carolyn C. Jackson,Carolyn C. Jackson,Sevgi Pekcan,Zafer Caliskaner,Jaime Inostroza,Beatriz Tavares Costa-Carvalho,Jose Antonio Tavares de Albuquerque,Humberto García-Ortiz,Lorena Orozco,Tayfun Ozcelik,Ahmed Abid,Ismail Abderahmani Rhorfi,Hicham Souhi,Hicham Naji Amrani,Adil Zegmout,Frederic Geissmann,Stephen W. Michnick,Ingrid Müller-Fleckenstein,Bernhard Fleckenstein,Anne Puel,Anne Puel,Anne Puel,Michael J. Ciancanelli,Nico Marr,Hassan Abolhassani,Hassan Abolhassani,María Elvira Balcells,Antonio Condino-Neto,Alexis Strickler,Katia Abarca,Cory Teuscher,Hans D. Ochs,Ismail Reisli,Esra Hazar Sayar,Jamila El-Baghdadi,Jacinta Bustamante,Lennart Hammarström,Lennart Hammarström,Lennart Hammarström,Stuart G. Tangye,Stuart G. Tangye,Sandra Pellegrini,Sandra Pellegrini,Lluis Quintana-Murci,Lluis Quintana-Murci,Laurent Abel,Laurent Abel,Laurent Abel,Jean-Laurent Casanova +94 more
TL;DR: Homozygosity for the catalytically inactive P1104A missense variant of the TYK2 Janus kinase selectively disrupts the induction of IFN-γ by IL-23 and is a common monogenic etiology of tuberculosis.
Journal ArticleDOI
Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency
Julien Cottineau,Molly C. Kottemann,Francis P. Lach,Young Hoon Kang,Frédéric Vély,Elissa K. Deenick,Tomi Lazarov,Laure Gineau,Yi Wang,Andrea Farina,Marie Chansel,Lazaro Lorenzo,Christelle Piperoglou,Cindy S. Ma,Patrick Nitschke,Aziz Belkadi,Yuval Itan,Bertrand Boisson,Fabienne Jabot-Hanin,Capucine Picard,Jacinta Bustamante,Celine Eidenschenk,Soraya Boucherit,Nathalie Aladjidi,Didier Lacombe,Pascal Barat,Waseem Qasim,Jane A. Hurst,Andrew J. Pollard,Holm H. Uhlig,Claire Fieschi,Jean Michon,Vladimir P. Bermudez,Laurent Abel,Jean-Pierre de Villartay,Frederic Geissmann,Stuart G. Tangye,Jerard Hurwitz,Eric Vivier,Jean-Laurent Casanova,Agata Smogorzewska,Emmanuelle Jouanguy +41 more
TL;DR: Autosomal recessive, partial GINS1 deficiency impairs DNA replication and underlies intra-uterine growth retardation, chronic neutropenia, and NK cell deficiency.
Journal ArticleDOI
Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency
Xiao-Fei Kong,Rubén Martínez-Barricarte,J. Kennedy,Federico Mele,Tomi Lazarov,Elissa K. Deenick,Elissa K. Deenick,Cindy S. Ma,Cindy S. Ma,Gaëlle Breton,Kimberly Lucero,David Langlais,Aziz Bousfiha,Aziz Bousfiha,Caner Aytekin,Janet Markle,Céline Trouillet,Fabienne Jabot-Hanin,Fabienne Jabot-Hanin,Cecilia S. Lindestam Arlehamn,Geetha Rao,Geetha Rao,Capucine Picard,Théo Lasseau,Daniela Latorre,Sophie Hambleton,Caroline Deswarte,Caroline Deswarte,Yuval Itan,Katia Abarca,Dewton Moraes-Vasconcelos,Fatima Ailal,Fatima Ailal,Aydan Ikinciogullari,Figen Dogu,Ibtihal Benhsaien,Ibtihal Benhsaien,Alessandro Sette,Alessandro Sette,Laurent Abel,Laurent Abel,Laurent Abel,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Stéphanie Boisson-Dupuis,Bernd Schröder,Bernd Schröder,Michel C. Nussenzweig,Michel C. Nussenzweig,Kang Liu,Frederic Geissmann,Stuart G. Tangye,Stuart G. Tangye,Philippe Gros,Federica Sallusto,Jacinta Bustamante,Jean-Laurent Casanova +56 more
TL;DR: Novel human mutations in the enzyme SPPL2A that result in selective accumulation of CD74 in a dendritic cell subset and lead to their death and the failure to mount effective TH1 responses are identified.