A
Ayala King
Researcher at University of Pennsylvania
Publications - 1
Citations - 1419
Ayala King is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Bcl-2-associated X protein & BH3 Mimetic ABT-737. The author has an hindex of 1, co-authored 1 publications receiving 1366 citations.
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The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.
Tullia Lindsten,Andrea J. Ross,Ayala King,Wei-Xing Zong,Jeffrey C. Rathmell,Helena Shiels,Eugen Ulrich,Katrina G. Waymire,Patryce L. Mahar,Kenneth A. Frauwirth,Yifeng Chen,Michael C. Wei,Vicki M. Eng,David M. Adelman,M. Celeste Simon,Averil Ma,Jeffrey A. Golden,Gerard I. Evan,Stanley J. Korsmeyer,Grant R. MacGregor,Craig B. Thompson +20 more
TL;DR: Bax and Bak have overlapping roles in the regulation of apoptosis during mammalian development and tissue homeostasis and are found to be developmentally normal and reproductively fit.