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Azra Raza
Researcher at Columbia University Medical Center
Publications - 213
Citations - 12160
Azra Raza is an academic researcher from Columbia University Medical Center. The author has contributed to research in topics: Myelodysplastic syndromes & Leukemia. The author has an hindex of 42, co-authored 204 publications receiving 10903 citations. Previous affiliations of Azra Raza include Catholic Medical Center & New York Medical College.
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Journal ArticleDOI
A Double-Blind, Placebo-Controlled Trial of Ruxolitinib for Myelofibrosis
Srdan Verstovsek,Ruben A. Mesa,Jason Gotlib,Richard S. Levy,Vikas Gupta,John F. DiPersio,John Catalano,Michael W. Deininger,Michael W. Deininger,Carole B. Miller,Richard T. Silver,Moshe Talpaz,Elliott F. Winton,Jimmie H. Harvey,Murat O. Arcasoy,Elizabeth O. Hexner,Roger M. Lyons,Ronald Paquette,Azra Raza,Kris Vaddi,Susan Erickson-Viitanen,Iphigenia L. Koumenis,William Sun,Victor Sandor,Hagop M. Kantarjian +24 more
TL;DR: Ruxolitinib provided significant clinical benefits in patients with myel ofibrosis by reducing spleen size, ameliorating debilitating myelofibrosis-related symptoms, and improving overall survival.
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Clinical effect of point mutations in myelodysplastic syndromes.
Rafael Bejar,Kristen E. Stevenson,Omar Abdel-Wahab,Naomi Galili,Björn Nilsson,Guillermo Garcia-Manero,Hagop M. Kantarjian,Azra Raza,Ross L. Levine,Donna Neuberg,Benjamin L. Ebert +10 more
TL;DR: Mutations in TP53, EZH2, ETV6, RUNX1, and ASXL1 are predictors of poor overall survival in patients with myelodysplastic syndromes, independently of established risk factors.
Journal ArticleDOI
Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion.
Alan F. List,Gordon W. Dewald,John M. Bennett,A. Giagounidis,Azra Raza,Eric J. Feldman,Bayard L. Powell,Peter L. Greenberg,Deborah A. Thomas,Richard Stone,Craig B. Reeder,Kenton Wride,John Patin,Michele Schmidt,Jerome B. Zeldis,Robert Knight +15 more
TL;DR: Lenalidomide can reduce transfusion requirements and reverse cytologic and cytogenetic abnormalities in patients who have the myelodysplastic syndrome with the 5q31 deletion.
Journal ArticleDOI
Identification of RPS14 as a 5q - syndrome gene by RNA interference screen
Benjamin L. Ebert,Jennifer Pretz,Jocelyn Bosco,Cindy Y. Chang,Pablo Tamayo,Naomi Galili,Azra Raza,David E. Root,Eyal C. Attar,Steven R. Ellis,Todd R. Golub,Todd R. Golub,Todd R. Golub +12 more
TL;DR: It is found that partial loss of function of the ribosomal subunit protein RPS14 phenocopies the disease in normal haematopoietic progenitor cells, and also that forced expression of RPS 14 rescues the disease phenotype in patient-derived bone marrow cells.
Journal ArticleDOI
Myelodysplastic syndromes: incidence and survival in the United States.
TL;DR: The first opportunity to examine the incidence and survival of patients with MDS in the United States using a large, population‐based database is examined.