Badri N. Pandey

TL;DR: This study revealed that, autocrine soluble factors regulate dual but differential role of ATF-2 as a transcription factor or DNA repair protein, which collectively culminate in radioresistance of A549 cells.

TL;DR: This review elucidates the effect of IR on various oncogenic RTKs and their mechanisms, downstream signaling, intracellular translocations, their role in the repair of radiation-induced DNA damage and post-irradiation survival, and identifies the radiosensitizing potential of recently developed RTK-targeted nanoformulations.

TL;DR: Amongst the chosen biocompatible agents, tiron, SLB, PA and L52 hold promise to enhance Th decorporation for human application.

TL;DR: Evaluation of plasma membrane fluidity and intracellular SOD with relation to apoptotic death of cervical carcinoma cells after radiation therapy suggests decrease in DPH polarization in membrane, reduction in SOD activity and increased apoptosis in cervical cells of cancer patients treated with radiation may be consequent to oxidative damage induced by reactive oxygen species.

TL;DR: An overview of research activities in the laboratory on the effects of thorium in human cells and animal models and the importance of multidisciplinary interactions to further understand the cellular and molecular basis of radiobiological effects ofThorium in mammalian systems is presented.