B
Baharak Bahmani
Researcher at Brigham and Women's Hospital
Publications - 30
Citations - 695
Baharak Bahmani is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Indocyanine green & Nanocapsules. The author has an hindex of 12, co-authored 28 publications receiving 493 citations. Previous affiliations of Baharak Bahmani include Amirkabir University of Technology & University of California, Riverside.
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Journal ArticleDOI
Intratumoral immunotherapy using platelet-cloaked nanoparticles enhances antitumor immunity in solid tumors
Baharak Bahmani,Hua Gong,Brian T. Luk,Kristofer J. Haushalter,Ethel DeTeresa,Mark Previti,Jiarong Zhou,Weiwei Gao,Jack D. Bui,Liangfang Zhang,Ronnie H. Fang,Jie Zhang +11 more
TL;DR: Treatment of an aggressive breast cancer model with intratumoral PNP-R848 delays tumor growth and inhibits lung metastasis and highlights the promise of locally delivering immunostimulatory payloads using biomimetic nanocarriers, which possess advantages such as enhanced biocompatibility and natural targeting affinities.
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Erythrocyte-derived photo-theranostic agents: hybrid nano-vesicles containing indocyanine green for near infrared imaging and therapeutic applications
TL;DR: This work demonstrates the first successful engineering of hybrid nano-scale constructs derived from membranes of hemoglobin-depleted erythrocytes that encapsulate the near infrared chromophore, indocyanine green and shows the utility of the constructs as photo-theranostic agents in fluorescence imaging and photothermal destruction of human cells.
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Coatings of polyethylene glycol for suppressing adhesion between solid microspheres and flat surfaces.
Srigokul Upadhyayula,Timothy Quinata,Stephen Bishop,Sharad Gupta,Noah R. Johnson,Baharak Bahmani,Kliment Bozhilov,Jeremy Stubbs,Pamela Jreij,Pratima Nallagatla,Valentine I. Vullev +10 more
TL;DR: The development and the examination of surface coatings that suppress the adhesion between glass surfaces and polymer microspheres suggest that such surfactant additives tend to be redundant and that covalently grafted coatings of PEGs with selected chain lengths provide sufficient suppression of nonspecific interfacial interactions.
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Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival
Baharak Bahmani,Mayuko Uehara,Liwei Jiang,Farideh Ordikhani,Naima Banouni,Takaharu Ichimura,Zhabiz Solhjou,Georg J. Furtmüller,Gerald Brandacher,David Alvarez,Ulrich H. von Andrian,Kenji Uchimura,Qiaobing Xu,Ishaan Vohra,Osman A. Yilmam,Yousef Haik,Jamil Azzi,Vivek Kasinath,Jonathan S. Bromberg,Martina M. McGrath,Reza Abdi +20 more
TL;DR: A nanoparticle (NP) is synthesized as a carrier of anti-CD3, and the conjugation strategy to coat the NP surface with MECA79 mAb (MECA79-anti- CD3-NP) to enhance LN accumulation is optimized to redefine the methods of administering immune therapeutics in transplantation.
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Functionalized polymeric nanoparticles loaded with indocyanine green as theranostic materials for targeted molecular near infrared fluorescence imaging and photothermal destruction of ovarian cancer cells.
Baharak Bahmani,Yadir Guerrero,Danielle Bacon,Vikas Kundra,Valentine I. Vullev,Bahman Anvari +5 more
TL;DR: This study investigates the effectiveness of a nano‐structured system for combined near infrared (NIR) fluorescence imaging of human epidermal growth factor receptor‐2 (HER2) over‐expression, as a biomarker of ovarian cancer cells, and photothermal destruction of these cells in vitro.