B
Baljit S. Moonga
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 79
Citations - 4767
Baljit S. Moonga is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Osteoclast & Bone resorption. The author has an hindex of 37, co-authored 79 publications receiving 4581 citations. Previous affiliations of Baljit S. Moonga include St George's Hospital & Veterans Health Administration.
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Journal ArticleDOI
FSH Directly Regulates Bone Mass
Li Sun,Yuanzhen Peng,Allison C. Sharrow,Allison C. Sharrow,Jameel Iqbal,Zhiyuan Zhang,Dionysios J. Papachristou,Dionysios J. Papachristou,Samir Zaidi,Ling-Ling Zhu,Beatrice B. Yaroslavskiy,Beatrice B. Yaroslavskiy,Hang Zhou,Alberta Zallone,M. Ram Sairam,T. Rajendra Kumar,Wei Bo,Jonathan Braun,Luis Cardoso-Landa,Mitchell B. Schaffler,Baljit S. Moonga,Harry C. Blair,Harry C. Blair,Mone Zaidi +23 more
TL;DR: It is suggested that high circulating FSH causes hypogonadal bone loss and that Osteoclasts and their precursors possess G(i2alpha)-coupled FSHRs that activate MEK/Erk, NF-kappaB, and Akt to result in enhanced osteoclast formation and function.
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Osteoclastic inhibition: an action of nitric oxide not mediated by cyclic GMP.
Iain MacIntyre,Mone Zaidi,A. S. M. T. Alam,Harish K. Datta,Baljit S. Moonga,P S Lidbury,Markus Hecker,John R. Vane +7 more
TL;DR: The results show that the autocoid is also a potent inhibitor of osteoclast function, and nitric oxide (NO) may be an important member of the latter group.
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Calcium-activated intracellular calcium elevation: a novel mechanism of osteoclast regulation
TL;DR: It is demonstrated here for the first time that the concentration of calcium ions at the resorptive site directly regulates osteoclast function by modulating the intracellular free calcium concentration.
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Stimulation of osteoclastic bone resorption by hydrogen peroxide
Bridget E. Bax,A. S. M. Towhidul Alam,Bashab Banerji,Christopher M.R. Bax,Peter J.R. Bevis,Clifford Robert Stevens,Baljit S. Moonga,David Russell Blake,Mone Zaidi +8 more
TL;DR: This paper found that hydrogen peroxide (H2O2), a reactive oxygen species (ROS), is a potent stimulator of osteoclastic bone resorption and cell motility.
Journal ArticleDOI
A new function for CD38/ADP-ribosyl cyclase in nuclear Ca2+ homeostasis.
Olugbenga A. Adebanjo,Hindupur K. Anandatheerthavarada,Antoliy Koval,Baljit S. Moonga,Baljit S. Moonga,Gopa Biswas,Li Sun,Li Sun,Bali R. Sodam,Bali R. Sodam,Peter J. R. Bevis,Peter J. R. Bevis,C. L.-H. Huang,Solomon Epstein,Lai Fa,Narayan G. Avadhani,Mone Zaidi +16 more
TL;DR: The existence in the inner nuclear membrane of a functionally active CD38/ADP-ribosyl cyclase that has its catalytic site within the nucleoplasm is reported and it is proposed that the enzyme catalyses the intranuclear cyclization of nicotinamide adenine dinucleotide to cyclic adenosine diphosphate ribose.