B
Bandaru S. Reddy
Researcher at Rutgers University
Publications - 277
Citations - 28225
Bandaru S. Reddy is an academic researcher from Rutgers University. The author has contributed to research in topics: Azoxymethane & Colorectal cancer. The author has an hindex of 97, co-authored 277 publications receiving 27634 citations. Previous affiliations of Bandaru S. Reddy include Pharmacia & Dana Corporation.
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Preclinical efficacy evaluation of potential chemopreventive agents in animal carcinogenesis models: Methods and results from the NCI chemoprevention drug development program
Vernon E. Steele,Richard C. Moon,Lubet Ra,Clinton J. Grubbs,Bandaru S. Reddy,Michael J. Wargovich,David L. McCormick,M. A. Pereira,James A. Crowell,Donya Bagheri +9 more
TL;DR: This paper summarizes the results of 144 agents in 352 tests using various animal efficacy models, representing 85 different agents, that were positive for efficacy against chemical carcinogen–induced tumors in animal models.
Journal Article
Preventive Potential of Wheat Bran Fractions against Experimental Colon Carcinogenesis: Implications for Human Colon Cancer Prevention
Bandaru S. Reddy,Yoshinobu Hirose,Leonard A. Cohen,Barbara Simi,Indrane Cooma,Chinthalapally V. Rao +5 more
TL;DR: It is demonstrated for the first time that the lipid fraction of wheat bran has strong colon tumor inhibitor properties, and the specific WB fractions such as WB fiber, WB lipids, or phytic acid differentially affect colon carcinogenesis in a well-established colon cancer model.
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Dietary fat and colon cancer: Animal model studies
TL;DR: L Laboratory animal model studies demonstrated that not only the amount of rat, but also types of fat differing in fatty acid composition are important determining factors in colon tumor development.
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Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable
Rong Hu,Tin Oo Khor,Guoxiang Shen,Woo-Sik Jeong,Vidya Hebbar,Chi Chen,Changjiang Xu,Bandaru S. Reddy,Kiran Chada,Ah-Ng Tony Kong +9 more
TL;DR: Measurement of SFN and its metabolite SFN-GSH in the small intestine using LC-MS indicates that the concentrations between 3 and 30 nmol/g are required to prevent, or retard adenoma formation in the gastrointestinal tract of ApcMin/+ mice.
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Possible mechanisms by which pro- and prebiotics influence colon carcinogenesis and tumor growth.
TL;DR: Dietary administration of oligofructose and inulin inhibits the development of ACF in the colon, suggesting the potential colon tumor inhibitory properties of chicory fructans.