B
Baoli Yang
Researcher at University of Iowa
Publications - 77
Citations - 7167
Baoli Yang is an academic researcher from University of Iowa. The author has contributed to research in topics: Glia maturation factor & Gene. The author has an hindex of 38, co-authored 76 publications receiving 6645 citations. Previous affiliations of Baoli Yang include Roy J. and Lucille A. Carver College of Medicine & University of North Carolina at Chapel Hill.
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Journal ArticleDOI
The mammalian sodium channel BNC1 is required for normal touch sensation.
Margaret P. Price,Gary R. Lewin,Sabrina L. McIlwrath,Chun Cheng,Jinghui Xie,Paul A. Heppenstall,Cheryl L. Stucky,Annne G. Mannsfeldt,Timothy J. Brennan,Heather A. Drummond,Jing Qiao,Christopher J. Benson,Delrdre E. Tarr,Ron F. Hrstka,Baoli Yang,Roger A. Williamson,Michael J. Welsh +16 more
TL;DR: It is shown that disrupting the mouse BNC1 gene markedly reduces the sensitivity of a specific component of mechanosensation: low-threshold rapidly adapting mechanoreceptors, and this data identify the B NC1 channel as essential for the normal detection of light touch and indicate that BNC 1 may be a central component of a mechanosensory complex.
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Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development
James L. Clements,Baoli Yang,Susan E. Ross-Barta,Steve Eliason,Ronald F. Hrstka,Roger A. Williamson,Gary A. Koretzky +6 more
TL;DR: The leukocyte-specific adapter molecule SLP-76 plays a crucial role in translating signals mediated by pre-T cell receptors into distal biochemical events and is required for normal thymocyte development.
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Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin
Darryl Y. Nishimura,Melissa A. Fath,Robert F. Mullins,Charles Searby,Michael P. Andrews,Roger J. Davis,Jeaneen L. Andorf,Kirk Mykytyn,Ruth E. Swiderski,Baoli Yang,Rivka Carmi,Edwin M. Stone,Val C. Sheffield +12 more
TL;DR: It is demonstrated that BBS2 retinopathy involves normal retina development followed by apoptotic death of photoreceptors, the primary ciliated cells of the retina, indicating a defect in transport.
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Bardet-Biedl syndrome type 4 (BBS4)-null mice implicate Bbs4 in flagella formation but not global cilia assembly.
Kirk Mykytyn,Robert F. Mullins,Michael P. Andrews,Annie P. Chiang,Ruth E. Swiderski,Baoli Yang,Terry A. Braun,Thomas L. Casavant,Edwin M. Stone,Val C. Sheffield +9 more
TL;DR: It is shown that mice lacking the Bbs4 protein have major components of the human phenotype, including obesity and retinal degeneration, and homology comparisons of BBS proteins in model organisms find that they are specifically conserved in ciliated organisms.
Journal ArticleDOI
Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 ( Irf6 )
Christopher R. Ingraham,Akira Kinoshita,Shinji Kondo,Baoli Yang,Samin A. Sajan,Kurt J. Trout,Margaret Malik,Martine Dunnwald,Stephen L. Goudy,Michael Lovett,Jeffrey C. Murray,Brian C. Schutte +11 more
TL;DR: It is reported that mice deficient for Irf6 have abnormal skin, limb and craniofacial development, and Histological and gene expression analyses indicate that the primary defect is in keratinocyte differentiation and proliferation.