B
Barry Gold
Researcher at University of Pittsburgh
Publications - 102
Citations - 2422
Barry Gold is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: DNA & Base pair. The author has an hindex of 29, co-authored 102 publications receiving 2336 citations. Previous affiliations of Barry Gold include University of Nebraska Medical Center & Eppley Institute for Research in Cancer and Allied Diseases.
Papers
More filters
Journal Article
Inhibition of ultraviolet light induced skin carcinogenesis in SKH-1 mice by apigenin, a plant flavonoid
TL;DR: Apigenin did not prevent the in vitro production of photoproducts in salmon sperm DNA suggesting that apigen in did not inhibit UVA/B induced ODC activity or UVB induced skin carcinogenesis by simply absorbing ultraviolet light or decreasing DNA damage.
Journal ArticleDOI
p53 mutants can often transactivate promoters containing a p21 but not Bax or PIG3 responsive elements.
Paola Campomenosi,Paola Monti,Anna Aprile,Angelo Abbondandolo,Angelo Abbondandolo,Thierry Frebourg,Barry Gold,Tim Crook,Alberto Inga,Alberto Inga,Michael A. Resnick,Richard Iggo,Gilberto Fronza +12 more
TL;DR: The transactivation ability of 77 p53 mutants is determined using reporter yeast strains containing a p53-regulated ADE2 gene whose promoter is regulated by p53 responsive elements derived from the regulatory region of the p21, Bax and PIG3 genes.
Journal ArticleDOI
Mimosine inhibits viral dna synthesis through ribonucleotide reductase
TL;DR: It is found that mimosine-treated cells had a reduction in the pools of dGTP and dATP and that Mimosine inhibited ribonucleotide reductase in vitro in an iron-dependent manner.
Journal ArticleDOI
An unprecedented nucleic acid capture mechanism for excision of DNA damage
TL;DR: Crystal structures of the recently discovered Bacillus cereus AlkD glycosylase in complex with DNAs containing alkylated, mismatched and abasic nucleotides are presented, providing an illustration for how hydrolysis of N3- and N7-alkylated bases may be facilitated by increased lifetime out of the DNA helix.
Journal ArticleDOI
Characterization of DNA with an 8-oxoguanine modification
Sreelekha K. Singh,Marta W. Szulik,Manjori Ganguly,Irine Khutsishvili,Michael P. Stone,Luis A. Marky,Barry Gold +6 more
TL;DR: Thermodynamic studies show that oxoG destabilizes DNA (ΔΔG of 2–8 kcal mol−1 over a 16–116 mM NaCl range) due to a significant reduction in the enthalpy term, and has a profound effect on the level and nature of DNA hydration indicating that the environment around anOxoG•C is fundamentally different than that found at G•C.