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Bernard Piqueras
Researcher at Centre national de la recherche scientifique
Publications - 15
Citations - 1529
Bernard Piqueras is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Immune system & Acquired immune system. The author has an hindex of 9, co-authored 15 publications receiving 1451 citations. Previous affiliations of Bernard Piqueras include Curie Institute & Baylor University.
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Journal ArticleDOI
Gene expression patterns in blood leukocytes discriminate patients with acute infections
Octavio Ramilo,Octavio Ramilo,Windy Allman,Wendy K. Chung,Wendy K. Chung,Asuncion Mejias,Asuncion Mejias,Monica Ardura,Monica Ardura,Casey Glaser,Knut M. Wittkowski,Bernard Piqueras,Jacques Banchereau,A. Karolina Palucka,Damien Chaussabel +14 more
TL;DR: In this paper, gene expression profiles were obtained for 131 peripheral blood samples from pediatric patients with acute infections caused by influenza A virus, Gram-negative (Escherichia coli) or Gram-positive (Staphylococcus aureus and Streptococcus pneumoniae) bacteria.
Journal ArticleDOI
Common variable immunodeficiency patient classification based on impaired B cell memory differentiation correlates with clinical aspects.
Bernard Piqueras,C. Lavenu-Bombled,Lionel Galicier,F.Bergeron-Van Der Cruyssen,Luc Mouthon,S. Chevret,Patrice Debré,Christian Schmitt,Eric Oksenhendler +8 more
TL;DR: Different putative mechanisms responsible for impaired B cell activation and memory differentiation in this syndrome are proposed by analyzing B cell phenotype, immunoglobulin transcript expression, and somatic mutations.
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Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors.
TL;DR: It is shown that influenza virus triggers, in human blood dendritic-cell (DC) subsets, a coordinated chemokine (CK) secretion program with 3 successive waves that allows for a coordinated attraction of the different immune effectors in response to viral infection.
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CD2 Distinguishes Two Subsets of Human Plasmacytoid Dendritic Cells with Distinct Phenotype and Functions
Toshimichi Matsui,John E. Connolly,Mark A. Michnevitz,Damien Chaussabel,Chun I. Yu,Casey Glaser,Sasha Tindle,Marc Pypaert,Heidi Freitas,Bernard Piqueras,Jacques Banchereau,A. Karolina Palucka +11 more
TL;DR: It is shown that activated human pDCs inhibit replication of cancer cells and kill them in a contact-dependent fashion.
Journal ArticleDOI
Human Dendritic Cell Subsets for Vaccination
Peter Dubsky,Hideki Ueno,Bernard Piqueras,John E. Connolly,Jacques Banchereau,A. Karolina Palucka +5 more
TL;DR: Increased understanding of dendritic cells pathophysiology will permit their rational manipulation for therapy such as vaccination to improve immunity.