Bernhard Kuster

TL;DR: Gene ontology enrichment analysis showed evidence for stimulus-induced alterations of the saliva proteome to boot an efficient molecular defense network of the oral cavity, and microbial growth experiments clearly demonstrated for the first time that the increase of the salivary lysozyme abundance upon oral citric acid stimulation translates into an enhanced biological function.

TL;DR: This is one of the most comprehensive transcriptomic and proteomic studies of native and propagated HUVEC, which underscores the importance of the morphology of the cellular microenvironment to regulate cellular differentiation, and demonstrates, for the first time, the potential of Xellulin as versatile tool promoting an in vivo-like phenotype in primary and propagate cell culture.

TL;DR: Quantitative chemical proteomics reveals a Plk1 inhibitor-compromised cell death pathway in human cells that is linked to cell death in animals and humans.

TL;DR: This study highlights the intrinsic adaption of L. sakei to plant environments, where sucrose is abundant, and provides fundamental knowledge regarding the use of L., sakei as starter culture for sucrose-based food fermentation processes with in-situ dextran formation.

TL;DR: A novel version of Kinobeads is reported that extends kinome coverage to native protein kinases from cell line or tissue lysates and shows that NVP-BEZ235 is not a PI3K inhibitor, and the utility of the new affinity matrix is demonstrated by the profiling of 13 clinical and preclinical PIKK/PI3K inhibitors.