Berry Birdsall

TL;DR: Total internal reflection fluorescence microscopy in living cells to visualize thousands of individual molecules of a model GPCR, the M1 muscarinic acetylcholine receptor, established the dynamic nature of dimer formation with M1 receptors undergoing interconversion between monomers and dimers on the timescale of seconds.

TL;DR: A general semiempirical correction procedure which can be used for absorbance values as high as 5 is described and the importance of choosing the excitation wavelength so as to minimize the necessity for these corrections is emphasized.

TL;DR: Recognition surfaces for antibodies that inhibit processing and invasion, and antibodies that block the binding of these inhibitory antibodies, have been mapped on the three-dimensional structure by considering specific MSP-1 mutants.

TL;DR: In this article, site-directed mutagenesis was used to change specific amino acid residues in Merozoite surface protein 1 (MSP-1) and abolish antibody binding.

TL;DR: In this paper, a method for the study of the conformation in solution of small molecules bound to proteins was proposed for the binding of trimethoprim and NADP +, respectively, to Lactobacillus casei dihydrofolate reductase.