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Bertram Pitt

Researcher at University of Michigan

Publications -  834
Citations -  88351

Bertram Pitt is an academic researcher from University of Michigan. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 107, co-authored 754 publications receiving 78458 citations. Previous affiliations of Bertram Pitt include Rutgers University & Tufts Medical Center.

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Evaluation of the efficacy and safety of RLY5016, a polymeric potassium binder, in a double-blind, placebo-controlled study in patients with chronic heart failure (the PEARL-HF) trial

TL;DR: RLY5016 prevented hyperkalaemia and was relatively well tolerated in patients with HF receiving standard therapy and spironolactone and a non-absorbed, orally administered, potassium [K+]-binding polymer.
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Evidence of endothelial dysfunction in angiographically normal coronary arteries of patients with coronary artery disease.

TL;DR: The vasoconstrictive effect of acetylcholine in the angiographically normal coronary arteries of patients with CAD suggests the presence of a diffuse abnormality of endothelial function.
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Effect of Patiromer on Serum Potassium Level in Patients With Hyperkalemia and Diabetic Kidney Disease: The AMETHYST-DN Randomized Clinical Trial.

TL;DR: Patiromer was titrated to achieve and maintain serum potassium level 5.0 mEq/L or lower, which was the most common treatment-related adverse event, mild to moderate constipation, and hypokalemia (<3.3%) over the 52 weeks.
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Prognostic Importance of Impaired Systolic Function in Heart Failure With Preserved Ejection Fraction and the Impact of Spironolactone.

TL;DR: Impaired LS represents a novel imaging biomarker to identify patients with HFpEF at particularly high risk for cardiovascular morbidity and mortality and is a powerful predictor of HF hospitalization, cardiovascular death, or aborted cardiac arrest independent of clinical predictors.