B
Bertram Pitt
Researcher at University of Michigan
Publications - 834
Citations - 88351
Bertram Pitt is an academic researcher from University of Michigan. The author has contributed to research in topics: Heart failure & Myocardial infarction. The author has an hindex of 107, co-authored 754 publications receiving 78458 citations. Previous affiliations of Bertram Pitt include Rutgers University & Tufts Medical Center.
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Journal ArticleDOI
Impact of mineralocorticoid receptor antagonists on the risk of sudden cardiac death in patients with heart failure and left-ventricular systolic dysfunction: an individual patient-level meta-analysis of three randomized-controlled trials.
Xavier Rossello,Xavier Rossello,Cono Ariti,Cono Ariti,Stuart J. Pocock,Stuart J. Pocock,João Pedro Ferreira,Nicolas Girerd,John J.V. McMurray,Dirk J. van Veldhuisen,Bertram Pitt,Faiez Zannad +11 more
TL;DR: MRAs reduce the risk for SCD by 23% in patients with heart failure and LVSD, and the use of MRAs, on top of other evidence-based medications, should be optimized.
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Baseline characteristics in the Avoiding Cardiovascular events through Combination therapy in Patients Living with Systolic Hypertension (ACCOMPLISH) trial: A hypertensive population at high cardiovascular risk
Michael A. Weber,George L. Bakris,Björn Dahlöf,Bertram Pitt,Eric J. Velazquez,Jitendra Gupte,Martin Lefkowitz,Allen Hester,Victor Shi,Matthew R. Weir,Sverre E. Kjeldsen,Barry M. Massie,Shawna D. Nesbitt,Elizabeth Ofili,Kenneth Jamerson +14 more
TL;DR: It is noteworthy that the mean BMI of 31 in this cohort is clearly above the accepted diagnostic criterion of obesity and that 60% of patients are diabetic, possibly reflecting secular trends in clinical disease.
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Prospects for the use of antagonists to the platelet glycoprotein IIb/ IIIa receptor to prevent postangioplasty restenosis and thrombosis
Stephen G. Ellis,Eric R. Bates,Thomas F. Schaible,Harlan F. Weisman,Bertram Pitt,Eric J. Topol +5 more
TL;DR: Monoclonal antibodies and snake venom-derived or synthetic peptides directed against a common protein recognition sequence on the platelet glycoprotein IIb/IIIa receptor are currently in the early stages of preclinical and clinical testing and hold promise of preventing abrupt closure and restenosis by inhibiting platelet function.
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Vascular reactivity and high dietary eicopentaenoic acid
TL;DR: The contractile effect of norepinephrine in isolated rat aortic strips is normally augmented by intrinsic prostaglandins, and this augmentation is diminished by dietary intake of EPA.
Journal ArticleDOI
Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling.
Susanne W.M. van den Borne,Satoshi Isobe,H. Reinier Zandbergen,Peng Li,Artiom Petrov,Nathan D. Wong,Shinichiro Fujimoto,Ai Fujimoto,Dagfinn Lovhaug,Jos F.M. Smits,Mat J.A.P. Daemen,W. Matthijs Blankesteijn,Chris P. M. Reutelingsperger,Faiez Zannad,Navneet Narula,Mani A. Vannan,Bertram Pitt,Leonard Hofstra,Jagat Narula +18 more
TL;DR: The decrease in echocardiographic left ventricular function, strain and rotation parameters, as well as histologically verified deposition of thin collagen fibers, was significantly reduced in treatment groups and correlated with CRIP uptake.