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Beth L. Laube
Researcher at Johns Hopkins University
Publications - 97
Citations - 4356
Beth L. Laube is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Mucociliary clearance & Insulin. The author has an hindex of 35, co-authored 94 publications receiving 3953 citations. Previous affiliations of Beth L. Laube include Johns Hopkins University School of Medicine.
Papers
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Journal ArticleDOI
What the pulmonary specialist should know about the new inhalation therapies
Beth L. Laube,Hettie M. Janssens,F.H.C. de Jongh,Sunalene G. Devadason,Rajiv Dhand,Patrice Diot,Mark L. Everard,Ildiko Horvath,Paolo Navalesi,T. Voshaar,Henry Chrystyn +10 more
TL;DR: A collaboration of multidisciplinary experts on the delivery of pharmaceutical aerosols was facilitated by the European Respiratory Society and the International Society for Aerosols in Medicine to draw up a consensus statement with clear, up-to-date recommendations that enable the pulmonary physician to choose the type of aerosol delivery device that is most suitable for their patient.
Journal ArticleDOI
Potent bronchoprotective effect of deep inspiration and its absence in asthma.
TL;DR: It is demonstrated that bronchoprotection is a potent physiologic function of lung inflation and established its absence, even in mild asthma.
Journal ArticleDOI
ERS technical standard on bronchial challenge testing: General considerations and performance of methacholine challenge tests
Allan L. Coates,J. Wanger,Donald W. Cockcroft,Bruce H. Culver,Kai-Håkon Carlsen,Zuzana Diamant,Zuzana Diamant,Gail M. Gauvreau,Graham L. Hall,Teal S. Hallstrand,Ildiko Horvath,Frans H.C. de Jongh,Guy Joos,David A. Kaminsky,Beth L. Laube,Joerg D. Leuppi,Peter J. Sterk +16 more
TL;DR: This international task force report updates general considerations for bronchial challenge testing and the performance of the methacholine challenge test to include notable changes from prior recommendations in order to accommodate newer delivery devices.
Journal Article
The expanding role of aerosols in systemic drug delivery, gene therapy, and vaccination.
TL;DR: The continued expansion of the role of aerosol therapy will probably depend on demonstration of the safety of this route of administration for drugs that have their targets outside the lung and are administered long term, on the development of new drugs and drug carriers that can efficiently target hard-to-reach cell populations within the lungs of patients with disease, and on the developed of devices that improve aerosol delivery to infants.
Patent
Medication delivery system phase one
TL;DR: In this article, a rigid housing for inhaling pharmaceutical aerosols is described, where the patient is aided by having the initial velocity of the aerosolized medicine reduced to zero by virtue of the initial delivery of the same to the housing interior, and by maintaining the volumetric flow rate of the inhaled medication maintained below required limits.