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Beverly S. Muhlhausler
Researcher at Commonwealth Scientific and Industrial Research Organisation
Publications - 176
Citations - 6857
Beverly S. Muhlhausler is an academic researcher from Commonwealth Scientific and Industrial Research Organisation. The author has contributed to research in topics: Offspring & Adipose tissue. The author has an hindex of 41, co-authored 169 publications receiving 5740 citations. Previous affiliations of Beverly S. Muhlhausler include Flinders Medical Centre & Sewanee: The University of the South.
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Journal ArticleDOI
Critical evaluation of the Illumina MethylationEPIC BeadChip microarray for whole-genome DNA methylation profiling
Ruth Pidsley,Ruth Pidsley,Elena Zotenko,Elena Zotenko,Tim J Peters,Mitchell G. Lawrence,Gail P. Risbridger,Peter L. Molloy,Susan Van Djik,Beverly S. Muhlhausler,Clare Stirzaker,Clare Stirzaker,Susan J. Clark,Susan J. Clark +13 more
TL;DR: The EPIC array is a significant improvement over the HM450 array, with increased genome coverage of regulatory regions and high reproducibility and reliability, providing a valuable tool for high-throughput human methylome analyses from diverse clinical samples.
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Epigenetics and human obesity
TL;DR: It has become clear that several epigenetic marks are modifiable, by changing the exposure in utero, but also by lifestyle changes in adult life, which implies that there is the potential for interventions to be introduced in postnatal life to modify unfavourable epigenomic profiles.
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Developmental origins of adult health and disease: The role of periconceptional and foetal nutrition
I. Caroline McMillen,Severence M. MacLaughlin,Beverly S. Muhlhausler,Sheridan Gentili,Jaime L. Duffield,Janna L. Morrison +5 more
TL;DR: The evidence that such tradeoffs are anticipated from conception and that the periconceptional nutritional environment can programme the developmental trajectory of the stress axis and the systems that maintain and regulate arterial blood pressure is reviewed.
Journal ArticleDOI
Increased maternal nutrition alters development of the appetite-regulating network in the brain
Beverly S. Muhlhausler,Clare Lesley Adam,P.A. Findlay,Jaime A. Duffield,Isabella Caroline McMillen +4 more
TL;DR: Exposure to increased nutrition before birth alters the responses of the central appetite regulatory system to signals of increased adiposity after birth, suggesting that increased maternal nutrition alters development of the appetite‐regulating network in the brain.
Journal ArticleDOI
Early origins of obesity: programming the appetite regulatory system.
TL;DR: In this article, a review summarizes recent work on the expression and localization of the "appetite regulatory" peptides in the fetal rodent and sheep hypothalamus and their potential role in the early programming of postnatal appetite and obesity.