B
Billie Velapatiño
Researcher at Cayetano Heredia University
Publications - 25
Citations - 1344
Billie Velapatiño is an academic researcher from Cayetano Heredia University. The author has contributed to research in topics: Gene & Helicobacter pylori. The author has an hindex of 14, co-authored 21 publications receiving 1264 citations. Previous affiliations of Billie Velapatiño include Washington University in St. Louis & Family Research Institute.
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Journal ArticleDOI
Functional adaptation of BabA the H. pylori ABO blood group antigen binding adhesin
Marina Aspholm-Hurtig,Giedrius Dailide,Martina Lahmann,Awdhesh Kalia,Dag Ilver,Niamh Roche,Susanne Vikström,Rolf Sjöström,Sara Lindén,Anna Bäckström,Carina Lundberg,Anna Arnqvist,Jafar Mahdavi,Ulf J. Nilsson,Billie Velapatiño,Robert H. Gilman,Markus Gerhard,Teresa Alarcón,Manuel López-Brea,Teruko Nakazawa,James G. Fox,Pelayo Correa,Maria Gloria Dominguez-Bello,Guillermo I. Perez-Perez,Martin J. Blaser,Staffan Normark,Ingemar Carlstedt,Stefan Oscarson,Susann Teneberg,Douglas E. Berg,Thomas Borén +30 more
TL;DR: It is proposed that cycles of selection for increased and decreased bacterial adherence contribute to babA diversity and that these cycles have led to gradual replacement of generalist binding by specialist binding in blood group O–dominant human populations.
Journal ArticleDOI
Differences in Genotypes of Helicobacter pylori from Different Human Populations
Dangeruta Kersulyte,Asish K. Mukhopadhyay,Billie Velapatiño,Billie Velapatiño,WanWen Su,Zhi-jun Pan,C.M. Garcia,Virginia Hernandez,Yanet Valdez,Yanet Valdez,Rajesh S. Mistry,Robert H. Gilman,Yuan Yuan,Yuan Yuan,Hua Gao,Hua Gao,Teresa Alarcón,Manuel López-Brea,G. Balakrish Nair,Abhijit Chowdhury,Simanti Datta,Mutsunori Shirai,Teruko Nakazawa,Reidwaan Ally,Isidore Segal,Benjamin C.Y. Wong,Shiu Kum Lam,Farzad O. Olfat,Farzad O. Olfat,Thomas Borén,Lars Engstrand,Olga Torres,Roberto Schneider,Julian Thomas,Steven J. Czinn,Douglas E. Berg +35 more
TL;DR: Sequences in the cagA gene and in vacAm1 type alleles of the vacuolating cytotoxin gene (vacA) of strains from native Peruvians were also more like those from Spaniards than those from Asians, leading us to suggest that H. pylori infection might have become widespread in people quite recently in human evolution.
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Sequential Inactivation of rdxA (HP0954) and frxA (HP0642) Nitroreductase Genes Causes Moderate and High-Level Metronidazole Resistance in Helicobacter pylori
Jy Jeong,Asish K. Mukhopadhyay,Daiva Dailidiene,Ya-Ting Wang,Billie Velapatiño,Billie Velapatiño,Robert H. Gilman,Alan J. Parkinson,G. B. Nair,Bcy Wong,Shiu Kum Lam,Rajesh S. Mistry,Issy Segal,Y Yuan,Y Yuan,H Gao,H Gao,Teresa Alarcón,ML Brea,Yoshiyuki Ito,Dangeruta Kersulyte,Hae Kyung Lee,Y Gong,Avery Goodwin,Paul S. Hoffman,Douglas E. Berg +25 more
TL;DR: It is concluded that most MtZ resistance in H. pylori depends on rdxA inactivation, that mutations in frxA can enhance resistance, and that genes that confer Mtz resistance without rdx a inactivation are rare or nonexistent in H.'s pylOR populations.
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Helicobacter pylori Reinfection Is Common in Peruvian Adults after Antibiotic Eradication Therapy
Giselle Soto,Christian T. Bautista,Daniel E. Roth,Robert H. Gilman,Billie Velapatiño,Masako Ogura,Giedrius Dailide,Manuel Razuri,Rina Meza,Uriel Katz,Uriel Katz,Thomas P. Monath,Douglas E. Berg,David N. Taylor +13 more
TL;DR: Although eradication with antibiotics was successful, the high rate of reinfection suggests that treatment is unlikely to have a lasting public health effect in this setting, and neither prior eradication nor the memory immune response measurably alters the risk or burden of recurrent infection.
Journal ArticleDOI
Cluster of Type IV Secretion Genes in Helicobacter pylori's Plasticity Zone
Dangeruta Kersulyte,Billie Velapatiño,Asish K. Mukhopadhyay,Lizbeth Cahuayme,Alejandro Bussalleu,Juan M. Combe,Robert H. Gilman,Douglas E. Berg +7 more
TL;DR: A new 16.3-kb segment is described, 7 of whose 16 open reading frames are homologs of type IV secretion genes (virB4, virB7 to virB11, and virD4), the third such putative secretion gene cluster found in H. pylori.