Bingfang Yan

TL;DR: The design of a near-infrared light-induced transformative nanoparticle platform that combines photothermal ablation with immunotherapy and is more effective than either immunotherapy or photothermal therapy alone against primary treated and distant untreated tumors in a mouse breast cancer model is reported.

TL;DR: Con concurrent use of both drugs would inhibit the activation of oseltamivir, thus making this antiviral agent therapeutically inactive, which is epidemiologically of significance because people who receive osel Tamsivir and clopidogrel simultaneously may maintain susceptibility to influenza infection or a source of spreading influenza virus if already infected.

TL;DR: Comparison of hollow CuS nanoparticles with hollow gold nanospheres in similar particle sizes and morphology following intravenous administration to mice will advance the development of HCuSNPs as a new class of biodegradable inorganic nanomaterials for photothermal therapy.

TL;DR: The isoform-specific hydrolysis of aspirin and clopidogrel suggests that these two antithrombogenic agents may have pharmacokinetic interactions with different sets of ester drugs, and the altered Hydrolysis by polymorphic mutants provides a molecular explanation to the interindividual variation.

TL;DR: CYP2B6 is highly inducible by known CYP3A4 inducers and hPXR is a major determinant of CYP2B 6-inducible expression for many, but not all, compounds evaluated in this study.