Fatemeh Akhlaghi

TL;DR: The effects of NAFLD on the regulation, expression and activity of major DMEs and transporters are summarized and the potential mechanisms underlying these alterations are discussed.

TL;DR: Con concurrent use of both drugs would inhibit the activation of oseltamivir, thus making this antiviral agent therapeutically inactive, which is epidemiologically of significance because people who receive osel Tamsivir and clopidogrel simultaneously may maintain susceptibility to influenza infection or a source of spreading influenza virus if already infected.

TL;DR: CSF penetrance of d5, exogenous OT delivered by IN and IV administration is demonstrated and suggests that peripheral administration of OT does not lead to central release of endogenous OT, and that IN administration offered an advantage compared to IV administration with respect to achieving greater CSF concentrations of OT.

TL;DR: A marine gram-positive bacterium is presented that secretes secondary metabolites capable of quenching quorum sensing-controlled behaviors in several gram-negative reporter strains, and it is shown that these nontoxic metabolites may act as antagonists of bacterial quorum sensed by competing with N-acyl homoserine lactones for receptor binding.

TL;DR: The distribution characteristics of cyclosporin in blood, plasma and various tissues are clinically important and mathematical models that calculate CsAfu, and hence CsAU, from the concentration of plasma lipoproteins may be a more practical option and should provide a more accurate correlate of effectiveness and toxicity of this drug in transplant recipients than do conventional monitoring procedures.