B
Bo Lu
Researcher at Ohio State University
Publications - 390
Citations - 24905
Bo Lu is an academic researcher from Ohio State University. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 58, co-authored 353 publications receiving 21823 citations. Previous affiliations of Bo Lu include Wuhan University of Technology & Wuhan University.
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Radiosensitization of solid tumors by Z-VAD, a pan-caspase inhibitor
TL;DR: This preclinical study supports the therapeutic potential of Z-VAD as a radiosensitizer in breast and lung cancer and suggests caspase inhibition as a promising strategy to enhance the therapeutic ratio of radiation therapy in solid tumors.
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Serious psychological distress among persons with epilepsy based on the 2005 California Health Interview Survey.
TL;DR: To compare the prevalence of self‐reported serious psychological distress using the Kessler 6 in persons with a history of epilepsy (PWE) to those without epilepsy from a population‐based survey, the K6 is used.
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AT-101, a pan-Bcl-2 inhibitor, leads to radiosensitization of non-small cell lung cancer.
TL;DR: Investigations suggest that the Bcl-2 family may serve as effective therapeutic targets in lung cancer and further clinical studies are warranted to assess the potential of AT-101 as an agent that enhances the therapeutic ratio of radiotherapy in Lung cancer.
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BV6, an IAP Antagonist, Activates Apoptosis and Enhances Radiosensitization of Non-Small Cell Lung Carcinoma in Vitro
Wenyan Li,Bo Li,Nicholas J. Giacalone,Artour Torossian,Yunguang Sun,Kathy Niu,Opal Lin-Tsai,Bo Lu +7 more
TL;DR: BV6, an IAP antagonist, significantly enhanced the radiosensitization of HCC193 and H460 cells in vitro, and more research is warranted to test the mechanism of action of BV6 and to assess its potential in vivo and in the clinical setting.
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Inhibition of Survivin and Aurora B Kinase Sensitizes Mesothelioma Cells by Enhancing Mitotic Arrests
Kwang Woon Kim,Robert W. Mutter,Christopher D. Willey,Ty K. Subhawong,Eric T. Shinohara,Jeffrey M. Albert,Geng Ling,Carolyn Cao,Young Jin Gi,Bo Lu +9 more
TL;DR: Inhibition of survivin and Aurora B induces mitotic cell arrest in mesothelioma cells after irradiation, and these two proteins may be potential therapeutic targets for the enhancement of radiotherapy in malignant pleural mesotHelioma.