B
Bo Lu
Researcher at Ohio State University
Publications - 390
Citations - 24905
Bo Lu is an academic researcher from Ohio State University. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 58, co-authored 353 publications receiving 21823 citations. Previous affiliations of Bo Lu include Wuhan University of Technology & Wuhan University.
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Journal ArticleDOI
Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer.
TL;DR: The report suggests that combined inhibition of apoptosis and mTOR during radiotherapy is a potential therapeutic strategy to enhance radiation therapy in patients with non-small cell lung cancer.
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Fabrication of supramolecular hydrogels for drug delivery and stem cell encapsulation.
TL;DR: The in vitro cell viability studies and the in vivo histological studies demonstrated that the hydrogels were non-cytotoxic and biocompatible, which indicated that thehydrogels prepared were promising candidates as injectable scaffolds for tissue engineering applications.
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Survivin As a Therapeutic Target for Radiation Sensitization in Lung Cancer
Bo Lu,Yi Mu,Carolyn Cao,Fenghua Zeng,Sylke Schneider,J. Tan,James O. Price,Jun Chen,Michael L. Freeman,Dennis E. Hallahan +9 more
TL;DR: It is found that 3 Gy significantly reduced survivin protein level in human umbilical vein endothelial cells (HUVECs) but not in tumor cell lines, which suggests that survivin may be a target for cancer therapy.
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Targeting brain metastases in ALK-rearranged non-small-cell lung cancer
TL;DR: Potential pathways to target ALK-rearranged brain metastases are discussed, including next generation ALK inhibitors with greater CNS penetration and mechanisms to overcome resistance.
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Galactosylated fluorescent labeled micelles as a liver targeting drug carrier
Wu Dequn,Bo Lu,Cong Chang,Chang-Sheng Chen,Tao Wang,Yuan-Yuan Zhang,Si-Xue Cheng,Xuejun Jiang,Xian-Zheng Zhang,Ren-Xi Zhuo +9 more
TL;DR: The in vivo study demonstrated the relative uptake of the micelles by liver is much higher than the other tissues, indicating that the galactosylated micells have great potential as a liver targeting drug carrier.