Y
Yu Lian
Researcher at Central South University
Publications - 9
Citations - 1783
Yu Lian is an academic researcher from Central South University. The author has contributed to research in topics: Cancer & Nasopharyngeal carcinoma. The author has an hindex of 8, co-authored 9 publications receiving 1374 citations. Previous affiliations of Yu Lian include Nanchang University & Chinese Ministry of Education.
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Journal ArticleDOI
Role of tumor microenvironment in tumorigenesis.
Maonan Wang,Jingzhou Zhao,Lishen Zhang,Fang Wei,Yu Lian,Yingfeng Wu,Zhaojian Gong,Shanshan Zhang,Jianda Zhou,Ke Cao,Xiayu Li,Wei Xiong,Guiyuan Li,Zhaoyang Zeng,Can Guo +14 more
TL;DR: This manuscript offers a more comprehensive overview of the primary functions of each component of the TME in cancer initiation, progression, and invasion and includes primary therapeutic targeting markers for each player.
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Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
Hao Bo,Zhaojian Gong,Wenling Zhang,Xiayu Li,Yong Zeng,Qianjin Liao,Pan Chen,Lei Shi,Yu Lian,Yizhou Jing,Ke Tang,Zheng Li,Yanhong Zhou,Ming Zhou,Bo Xiang,Xiaoling Li,Jianbo Yang,Jianbo Yang,Wei Xiong,Guiyuan Li,Zhaoyang Zeng +20 more
TL;DR: Proteomic and bioinformatics analyses suggested that AFAP1-AS1 affected the expression of several small GTPase family members and molecules in the actin cytokeratin signaling pathway and promoted cancer cell metastasis via regulation of actin filament integrity.
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AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis
Zhaoyang Zeng,Hao Bo,Zhaojian Gong,Yu Lian,Xiayu Li,Xiaoling Li,Wenling Zhang,Hao Deng,Ming Zhou,Shuping Peng,Guiyuan Li,Wei Xiong +11 more
TL;DR: The number of noncoding RNAs functionally implicated in lung cancer progression is extended and the role of AFAP1-AS1 is highlighted as potential prognostic biomarker and therapeutic target of lung cancer.
Journal ArticleDOI
Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway
Yu Lian,Yu Lian,Yu Lian,Fang Xiong,Fang Xiong,Liting Yang,Liting Yang,Hao Bo,Zhaojian Gong,Yumin Wang,Fang Wei,Fang Wei,Yanyan Tang,Yanyan Tang,Xiayu Li,Qianjin Liao,Qianjin Liao,Hui Wang,Ming Zhou,Ming Zhou,Bo Xiang,Bo Xiang,Xu Wu,Xu Wu,Li Yong,Li Yong,Xiaoling Li,Xiaoling Li,Xiang Chen,Guiyuan Li,Guiyuan Li,Can Guo,Can Guo,Zhaoyang Zeng,Zhaoyang Zeng,Wei Xiong,Wei Xiong +36 more
TL;DR: In this article, the role of actin filament-associated protein 1 antisense RNA 1 (AFAP1-AS1), a long noncoding RNA, is investigated in vitro and in vivo.
Journal ArticleDOI
Linking long non-coding RNAs and SWI/SNF complexes to chromatin remodeling in cancer.
Yanyan Tang,Yanyan Tang,Jinpeng Wang,Jinpeng Wang,Yu Lian,Yu Lian,Chunmei Fan,Ping Zhang,Yingfen Wu,Xiayu Li,Xiayu Li,Fang Xiong,Xiaoling Li,Xiaoling Li,Guiyuan Li,Guiyuan Li,Wei Xiong,Wei Xiong,Zhaoyang Zeng,Zhaoyang Zeng +19 more
TL;DR: A link between lncRNAs and the SWI/SNF complexes and their role in chromatin remodeling and gene expression regulation in cancer is summarized, thereby providing systematic information and a better understanding of carcinogenesis.