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Brent L. Williams
Researcher at Columbia University
Publications - 24
Citations - 2409
Brent L. Williams is an academic researcher from Columbia University. The author has contributed to research in topics: Microbiome & Chronic fatigue syndrome. The author has an hindex of 17, co-authored 23 publications receiving 1977 citations.
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Journal ArticleDOI
Impaired Carbohydrate Digestion and Transport and Mucosal Dysbiosis in the Intestines of Children with Autism and Gastrointestinal Disturbances
Brent L. Williams,Mady Hornig,Timothy Buie,Margaret L. Bauman,Myunghee Cho Paik,Ivan Wick,Ashlee Bennett,Omar Jabado,David L. Hirschberg,W. Ian Lipkin +9 more
TL;DR: Gen expression and the mucoepithelial microbiota in intestinal biopsies from children with autism and gastrointestinal disease and children with gastrointestinal disease alone indicate a relationship between human intestinal gene expression and bacterial community structure and may provide insights into the pathophysiology of gastrointestinal disturbances in children with Autism.
Journal ArticleDOI
Application of Novel PCR-Based Methods for Detection, Quantitation, and Phylogenetic Characterization of Sutterella Species in Intestinal Biopsy Samples from Children with Autism and Gastrointestinal Disturbances
TL;DR: It is demonstrated that increased levels of Alcaligenaceae in intestinal biopsy samples from AUT-GI children result from the presence of high levels of members of the genus Sutterella, which elevates this little-recognized bacterium to the forefront.
Journal ArticleDOI
Genital Inflammation and the Risk of HIV Acquisition in Women
Lindi Masson,Lindi Masson,Jo-Ann S. Passmore,Jo-Ann S. Passmore,Lenine J. P. Liebenberg,Lise. Werner,Cheryl Baxter,Kelly B. Arnold,Carolyn Williamson,Carolyn Williamson,Francesca Little,Leila E. Mansoor,Vivek Naranbhai,Douglas A. Lauffenburger,Katharina Ronacher,Gerhard Walzl,Nigel Garrett,Brent L. Williams,Mara Couto-Rodriguez,Mady Hornig,W. Ian Lipkin,Anneke Grobler,Quarraisha Abdool Karim,Quarraisha Abdool Karim,Salim S. Abdool Karim,Salim S. Abdool Karim +25 more
TL;DR: Elevated genital concentrations of HIV target cell-recruiting chemokines and a genital inflammatory profile contributes to the high risk of HIV acquisition in these African women.
Journal ArticleDOI
Novel borna virus in psittacine birds with proventricular dilatation disease.
Kirsi S. Honkavuori,H. L. Shivaprasad,Brent L. Williams,Phenix Lan Quan,Mady Hornig,Craig Street,Gustavo Palacios,Stephen K. Hutchison,Monique França,Michael Egholm,Thomas Briese,W. Ian Lipkin +11 more
TL;DR: Pyrosequencing of cDNA from brains of parrots with proventricular dilatation disease showed 2 strains of a novel Borna virus, which confirmed virus presence in brain, proventriculus, and adrenal gland of 3 birds with PDD but not in 4 unaffected birds.
Journal ArticleDOI
Gut microbiomes of wild great apes fluctuate seasonally in response to diet
Allison L. Hicks,Kerry Jo Lee,Mara Couto-Rodriguez,Juber Patel,Rohini Sinha,Cheng Guo,Sarah H. Olson,Anton Seimon,Tracie A. Seimon,Tracie A. Seimon,Alain Ondzie,William B. Karesh,William B. Karesh,Patricia Reed,Kenneth N. Cameron,W. Ian Lipkin,Brent L. Williams +16 more
TL;DR: The data indicate that great ape microbiomes are malleable in response to dietary shifts, suggesting a role for microbiome plasticity in driving dietary flexibility, which may provide fundamental insights into the mechanisms by which diet has driven the evolution of human gut microbiomes.