K
Kelly B. Arnold
Researcher at University of Michigan
Publications - 50
Citations - 2366
Kelly B. Arnold is an academic researcher from University of Michigan. The author has contributed to research in topics: Immune system & Antibody. The author has an hindex of 21, co-authored 43 publications receiving 1680 citations. Previous affiliations of Kelly B. Arnold include Massachusetts Institute of Technology & University of Surrey.
Papers
More filters
Journal ArticleDOI
Genital Inflammation and the Risk of HIV Acquisition in Women
Lindi Masson,Lindi Masson,Jo-Ann S. Passmore,Jo-Ann S. Passmore,Lenine J. P. Liebenberg,Lise. Werner,Cheryl Baxter,Kelly B. Arnold,Carolyn Williamson,Carolyn Williamson,Francesca Little,Leila E. Mansoor,Vivek Naranbhai,Douglas A. Lauffenburger,Katharina Ronacher,Gerhard Walzl,Nigel Garrett,Brent L. Williams,Mara Couto-Rodriguez,Mady Hornig,W. Ian Lipkin,Anneke Grobler,Quarraisha Abdool Karim,Quarraisha Abdool Karim,Salim S. Abdool Karim,Salim S. Abdool Karim +25 more
TL;DR: Elevated genital concentrations of HIV target cell-recruiting chemokines and a genital inflammatory profile contributes to the high risk of HIV acquisition in these African women.
Journal ArticleDOI
Dissecting Polyclonal Vaccine-Induced Humoral Immunity against HIV Using Systems Serology.
Amy W. Chung,Amy W. Chung,Manu P. Kumar,Kelly B. Arnold,Wen-Han Yu,Wen-Han Yu,Matthew K. Schoen,Laura J. Dunphy,Todd J. Suscovich,Nicole Frahm,Caitlyn Linde,Alison E. Mahan,Michelle Hoffner,Hendrik Streeck,Hendrik Streeck,Margaret E. Ackerman,M. Juliana McElrath,Hanneke Schuitemaker,Maria G. Pau,Lindsey R. Baden,Lindsey R. Baden,Jerome H. Kim,Jerome H. Kim,Nelson L. Michael,Dan H. Barouch,Dan H. Barouch,Douglas A. Lauffenburger,Galit Alter +27 more
TL;DR: Multi-dimensional relational comparisons of vaccine humoral fingerprints offer a unique approach for the evaluation and design of novel vaccines against pathogens for which correlates of protection remain elusive.
Journal ArticleDOI
Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and an influx of HIV-susceptible target cells.
Kelly B. Arnold,Adam Burgener,Adam Burgener,Adam Burgener,Kenzie Birse,Kenzie Birse,Laura Romas,Laura Romas,Laura J. Dunphy,Kamnoosh Shahabi,Max Abou,Garrett Westmacott,Stuart McCorrister,Jessie Kwatampora,Billy Nyanga,Joshua Kimani,Joshua Kimani,Lindi Masson,Lindi Masson,Lenine J. P. Liebenberg,Salim S. Abdool Karim,Salim S. Abdool Karim,Jo-Ann S. Passmore,Jo-Ann S. Passmore,Jo-Ann S. Passmore,Douglas A. Lauffenburger,Rupert Kaul,Rupert Kaul,Rupert Kaul,Lyle R. McKinnon,Lyle R. McKinnon,Lyle R. McKinnon +31 more
TL;DR: Data reveal strong linkages between mucosal cytokines, barrier function, proteases, and immune cell movement, and propose these as potential mechanisms that increase risk of HIV acquisition.
Journal ArticleDOI
Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy
Siddappa N. Byrareddy,James Arthos,Claudia Cicala,Francois Villinger,Kristina Ortiz,Dawn M. Little,Neil Sidell,Maureen A. Kane,Jianshi Yu,Jace W. Jones,Philip J. Santangelo,Chiara Zurla,Lyle R. McKinnon,Kelly B. Arnold,Caroline E. Woody,Lutz Walter,Christian Roos,Angela Noll,Donald Van Ryk,Katija Jelicic,Raffaello Cimbro,Sanjeev Gumber,Michelle D. Reid,Volkan Adsay,Praveen K. Amancha,Ann E. Mayne,Tristram G. Parslow,Anthony S. Fauci,Aftab A. Ansari +28 more
TL;DR: Combining short-term antiretroviral therapy with specific anti-integrin treatment sustains low viral loads in monkeys and allows macaques to effectively control viremia and reconstitute their immune systems without a need for further therapy.
Journal ArticleDOI
Lung Microbiota Contribute to Pulmonary Inflammation and Disease Progression in Pulmonary Fibrosis.
David N O'Dwyer,Shanna L. Ashley,Stephen J. Gurczynski,Meng Xia,Carol A. Wilke,Nicole R. Falkowski,Katy C. Norman,Kelly B. Arnold,Gary B. Huffnagle,Margaret L. Salisbury,MeiLan K. Han,Kevin R. Flaherty,Eric S. White,Fernando J. Martinez,John R. Erb-Downward,Susan Murray,Bethany B. Moore,Robert P. Dickson +17 more
TL;DR: It is demonstrated that lung microbiota contribute to the progression of IPF, providing biological plausibility for the hypothesis that lung dysbiosis promotes alveolar inflammation and aberrant repair and Manipulation of lung microbiota may represent a novel target for the treatment of IPf.