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Brett K. Beaulieu-Jones
Researcher at Harvard University
Publications - 59
Citations - 3393
Brett K. Beaulieu-Jones is an academic researcher from Harvard University. The author has contributed to research in topics: Medicine & Deep learning. The author has an hindex of 16, co-authored 47 publications receiving 2147 citations. Previous affiliations of Brett K. Beaulieu-Jones include Brigham and Women's Hospital & Beth Israel Deaconess Medical Center.
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Proceedings ArticleDOI
Missing data imputation in the electronic health record using deeply learned autoencoders.
TL;DR: It is shown that despite clinical heterogeneity, ALS disease progression appears homogenous with time from onset being the most important predictor.
Journal ArticleDOI
Reproducibility of computational workflows is automated using continuous analysis
TL;DR: The development of continuous analysis is reported, a workflow that enables reproducible computational analyses and allows reviewers, editors or readers to verify reproducibility without manually downloading and rerunning code and can provide an audit trail for analyses of data that cannot be shared.
Journal ArticleDOI
International electronic health record-derived COVID-19 clinical course profiles: the 4CE consortium
Gabriel A. Brat,Griffin M. Weber,Nils Gehlenborg,Paul Avillach,Nathan Palmer,Luca Chiovato,James J. Cimino,Lemuel R. Waitman,Gilbert S. Omenn,Alberto Malovini,Jason H. Moore,Brett K. Beaulieu-Jones,Valentina Tibollo,Shawn N. Murphy,Sehi L'Yi,Mark Keller,Riccardo Bellazzi,David A. Hanauer,Arnaud Serret-Larmande,Alba Gutiérrez-Sacristán,John J. Holmes,John J. Holmes,Douglas S. Bell,Kenneth D. Mandl,Robert W Follett,Jeffrey G. Klann,Douglas A. Murad,Luigia Scudeller,Mauro Bucalo,Katie Kirchoff,Jean Craig,Jihad S. Obeid,Vianney Jouhet,Romain Griffier,Sébastien Cossin,Bertrand Moal,Lav P Patel,Antonio Bellasi,Hans U. Prokosch,Detlef Kraska,Piotr Sliz,Amelia L.M. Tan,Kee Yuan Ngiam,Alberto Zambelli,Danielle L. Mowery,Danielle L. Mowery,Emily Schiver,Batsal Devkota,Robert L. Bradford,Mohamad Daniar,Christel Daniel,Vincent Benoit,Romain Bey,Nicolas Paris,Patricia Serre,Nina Orlova,Julien Dubiel,Martin Hilka,Anne-Sophie Jannot,Stephane Breant,Judith Leblanc,Nicolas Griffon,Anita Burgun,Mélodie Bernaux,Arnaud Sandrin,Elisa Salamanca,Sylvie Cormont,Thomas Ganslandt,Tobias Gradinger,Julien Champ,Martin Boeker,Patricia Martel,Loic Esteve,Alexandre Gramfort,Olivier Grisel,Damien Leprovost,Thomas Moreau,Gaël Varoquaux,Jill-Jênn Vie,Demian Wassermann,Arthur Mensch,Charlotte Caucheteux,Christian Haverkamp,Guillaume Lemaitre,Silvano Bosari,Ian D. Krantz,Andrew M South,Tianxi Cai,Isaac S. Kohane +88 more
TL;DR: An international consortium of 96 hospitals across five countries formed an international consortium (4CE) to capture the trajectory of COVID-19 disease in patients and their response to interventions and established a framework to capture this trajectory.
Journal ArticleDOI
Characterizing and Managing Missing Structured Data in Electronic Health Records: Data Analysis.
Brett K. Beaulieu-Jones,Daniel R. Lavage,John W Snyder,Jason H. Moore,Sarah A. Pendergrass,Christopher R. Bauer +5 more
TL;DR: This study demonstrates how the mechanism of missingness can be assessed, evaluate the performance of a variety of imputation methods, and describes some of the most frequent problems that can be encountered in dealing with missing EHR data.
Journal ArticleDOI
Examining the Use of Real-World Evidence in the Regulatory Process
Brett K. Beaulieu-Jones,Samuel G. Finlayson,William Yuan,Russ B. Altman,Isaac S. Kohane,Vinay Prasad,Kun-Hsing Yu +6 more
TL;DR: The advantages and limitations of Rwe are summarized, the key opportunities for RWE are identified, and the way forward to maximize the potential of RWE for regulatory purposes is pointed the wayforward.