Brian C. Clark

TL;DR: This article will give an update on both the biological and clinical literature on dynapenia-serving to best synthesize this translational topic, and propose a working decision algorithm for defining dynAPenia.

TL;DR: Evidence-based clinical practice guidelines for screening, diagnosis and management of sarcopenia from the task force of the International Conference on Sarcopenia and Frailty Research (ICSFR) are presented.

TL;DR: A broad overview on the underlying mechanisms associated with elderly skeletal muscle performance is provided and major implications for scientists, clinicians, and health professionals who are developing therapeutic interventions aiming to enhance muscle function and/or prevent mobility and physical limitations are developed.

TL;DR: The societal burden and determinants of the loss of physical function with advancing age, the physiologic mechanisms underlying dynapenia (muscle weakness in the elderly), and perspectives on related critical issues to be addressed are discussed.

TL;DR: The role of nutrition in the muscular and neurologic systems for the preservation of muscle strength throughout the life span is addressed and subclinical deficits in the structure and function of the nervous system and/or impairments in the intrinsic force-generating properties of skeletal muscle are identified.