Brian M. Tress

TL;DR: Alteplase was non-significantly associated with lower infarct growth and significantly associated with increased reperfusion in patients who had mismatch, and phase III trials beyond 3 h after treatment are warranted.

TL;DR: In this paper, Alteplase was shown to promote reperfusion and attenuate infarct growth in patients who have a mismatch in perfusion-weighted MRI (PWI) and diffusion weighted MRI (DWI).

TL;DR: Persistent hyperglycemia on serial glucose monitoring is an independent determinant of infarct expansion and is associated with worse functional outcome and an urgent need to study normalization of blood glucose after stroke.

TL;DR: Higher acute blood glucose in patients with perfusion‐diffusion mismatch was associated with greater acute‐subacute lactate production, which, in turn, was independently associated with reduced salvage of mismatch tissue, which support the need for randomized controlled trials of aggressive glycemic control in acute stroke.

TL;DR: This study demonstrates that hippocampal sclerosis can be identified on MRI with a high degree of sensitivity and specificity and correctly predicted the side of the epileptogenic temporal lobe in 72 cases, with 2 possible errors.