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Britney Y. Lau
Researcher at Sandia National Laboratories
Publications - 10
Citations - 1227
Britney Y. Lau is an academic researcher from Sandia National Laboratories. The author has contributed to research in topics: Bacterial genome size & Lysogenic cycle. The author has an hindex of 5, co-authored 9 publications receiving 776 citations.
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Journal ArticleDOI
IslandViewer 4: expanded prediction of genomic islands for larger-scale datasets.
Claire Bertelli,Matthew R. Laird,Kelly P. Williams,Britney Y. Lau,Gemma Hoad,Geoffrey L. Winsor,Fiona S. L. Brinkman +6 more
TL;DR: The release of IslandViewer 4 is reported, with novel features to accommodate the needs of larger-scale microbial genomics analysis, while expanding GI predictions and improving its flexible visualization interface.
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RNAcentral: a comprehensive database of non-coding RNA sequences.
Anton I. Petrov,Simon Kay,Ioanna Kalvari,Kevin L. Howe,Kristian Gray,Elspeth A. Bruford,Paul J. Kersey,Guy Cochrane,Robert D. Finn,Alex Bateman,Ana Kozomara,Sam Griffiths-Jones,Adam Frankish,Christian W Zwieb,Britney Y. Lau,Kelly P. Williams,Patricia P. Chan,Todd M. Lowe,Jamie J. Cannone,Robin R. Gutell,Magdalena A. Machnicka,Magdalena A. Machnicka,Janusz M. Bujnicki,Maki Yoshihama,Naoya Kenmochi,Benli Chai,James R. Cole,Maciej Szymanski,Wojciech M. Karlowski,Valerie Wood,Eva Huala,Tanya Z. Berardini,Yi Zhao,Runsheng Chen,Weimin Zhu,Maria D. Paraskevopoulou,Ioannis S. Vlachos,Artemis G. Hatzigeorgiou,Lina Ma,Zhang Zhang,Joern Puetz,Peter F. Stadler,Daniel McDonald,S. Basu,Petra Fey,Stacia R. Engel,J. Michael Cherry,Pieter-Jan Volders,Pieter Mestdagh,Jacek Wower,Michael B. Clark +50 more
TL;DR: A new species-specific identifiers that refer to unique RNA sequences within a context of single species are created in RNAcentral, a database of non-coding RNA (ncRNA) sequences that aggregates data from specialised ncRNAs resources and provides a single entry point for accessing ncRNA sequences of all nc RNA types from all organisms.
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Islander: a database of precisely mapped genomic islands in tRNA and tmRNA genes
TL;DR: The algorithm identifies tDNAs, finds fragments of those t DNAs in the same replicon and removes unlikely candidate islands through a series of filters, insisting that each island encode an integrase, and attachment site sequence identity is carefully noted; therefore, the database also serves in the study of integrase site-specificity and its evolution.
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Ends of the line for tmRNA-SmpB
TL;DR: It is validated recent identification of tmRNA homologs in oomycete mitochondria by finding partner genes from oomyCete nuclei that target SmpB to the mitochondrion and identifying a small number of complete, but often highly derived, bacterial genomes that appear to lack a functional copy of either the tm RNA or Smp B gene.
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New candidates for regulated gene integrity revealed through precise mapping of integrative genetic elements.
Catherine M Mageeney,Britney Y. Lau,Julian M Wagner,Corey M. Hudson,Joseph S. Schoeniger,Raga Krishnakumar,Kelly P. Williams +6 more
TL;DR: TIGER uses a comparative genomic, ping-pong BLAST approach, based on the principle that the IGE integration module (i.e. its int-attP region) is cohesive, to map IGEs with unprecedented precision and without attB site bias.