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Bruce Kupelnick

Researcher at Tufts Medical Center

Publications -  44
Citations -  7696

Bruce Kupelnick is an academic researcher from Tufts Medical Center. The author has contributed to research in topics: Randomized controlled trial & Clinical trial. The author has an hindex of 22, co-authored 44 publications receiving 7439 citations. Previous affiliations of Bruce Kupelnick include Harvard University & Tufts University.

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A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction.

TL;DR: Finding and analyzing all therapeutic trials in a given field has become such a difficult and specialized task that the clinical experts called on to summarize the evidence in a timely fashion need access to better databases and new statistical techniques to assist them.
Journal Article

K/DOQI Clinical Practice Guidelines on Hypertension and Antihypertensive Agents in Chronic Kidney Disease

Andrew S. Levey, +84 more
TL;DR: The purpose of the Executive Summary is to provide a "stand-alone" summary of the background, scope, methods, and key recommendations, as well as the complete text of the guideline statements.
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Cumulative Meta-Analysis of Therapeutic Trials for Myocardial Infarction

TL;DR: Cumulative meta-analysis of therapeutic trials facilitates the determination of clinical efficacy and harm and may be helpful in tracking trials, planning future trials, and making clinical recommendations for therapy.
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n−3 Fatty acids from fish or fish-oil supplements, but not α-linolenic acid, benefit cardiovascular disease outcomes in primary- and secondary-prevention studies: a systematic review

TL;DR: Evidence suggests that increased consumption of n-3 FAs from fish or fish-oil supplements, but not of alpha-linolenic acid, reduces the rates of all-cause mortality, cardiac and sudden death, and possibly stroke.
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Effects of omega-3 fatty acids on serum markers of cardiovascular disease risk: a systematic review

TL;DR: The evidence supports a dose-dependent beneficial effect of fish oil on serum triglycerides, particularly among people with more elevated levels, and fish oil consumption also modestly improves HDL cholesterol, increases LDL cholesterol levels, but does not appear to adversely affect glucose homeostasis.