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Bruno Canque
Researcher at École pratique des hautes études
Publications - 42
Citations - 1899
Bruno Canque is an academic researcher from École pratique des hautes études. The author has contributed to research in topics: Dendritic cell & Haematopoiesis. The author has an hindex of 19, co-authored 40 publications receiving 1821 citations. Previous affiliations of Bruno Canque include Institut national de la recherche scientifique & Centre national de la recherche scientifique.
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Journal ArticleDOI
The dielmo project: a longitudinal study of natural malaria infection and the mechanisms of protective immunity in a community living in a holoendemic area of senegal
Jean-François Trape,Christophe Rogier,Lassana Konate,Nafissatou Diagne,Hilaire Bouganali,Bruno Canque,Fabrice Legros,Assane Badji,Gora Ndiaye,Papa Ndiaye,Karima Brahimi,Ousmane Faye,Pierre Druilhe,Luiz Pereira da Silva +13 more
TL;DR: The findings suggest that sterile immunity and clinical protection are never fully achieved in humans continuously exposed since birth to intense transmission.
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Human Dendritic Cell Differentiation Pathway From CD34+ Hematopoietic Precursor Cells
TL;DR: This system results first in the differentiation of CD13hi precursors that strongly express DR and CD4, from which more mature CD1a+ DCs continuously differentiate all along the culture period.
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Infection of Dendritic Cells (DCs), Not DC-SIGN-Mediated Internalization of Human Immunodeficiency Virus, Is Required for Long-Term Transfer of Virus to T Cells
Laura Burleigh,Pierre-Yves Lozach,Cecile Schiffer,Isabelle Staropoli,Valérie Pezo,Françoise Porrot,Bruno Canque,Jean-Louis Virelizier,Fernando Arenzana-Seisdedos,Ali Amara +9 more
TL;DR: It is shown that endocytosis-defective DC-sign molecules enhance T-cell infection as efficiently as their wild-type counterparts, indicating that DC-SIGN-mediated HIV internalization is dispensable for trans-enhancement.
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Molecular characterization of early human T/NK and B-lymphoid progenitor cells in umbilical cord blood
Rima Haddad,Philippe Guardiola,Brigitte Izac,Christelle Thibault,Jerry Radich,Anne Lise Delezoide,Claude Baillou,François M. Lemoine,Jean Claude Gluckman,Françoise Pflumio,Bruno Canque +10 more
TL;DR: Comparison of the lymphoid potential of a novel umbilical cord blood population with that of a hematopoietic progenitor cell (HPC) population indicates that CD34(+)CD45RA(hi)CD7(+) and CD34 (+) CD45RA (hi)Lin(-)CD10(+) HPCs correspond to multipotent early lymphoid progenitors polarized toward either the T/NK or B lineage, respectively.
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Dynamics of Thymus-Colonizing Cells during Human Development
Rima Haddad,Fabien Guimiot,Emmanuelle Six,Frederic Jourquin,Niclas Setterblad,Edmond Kahn,Micael Yagello,Cecile Schiffer,Isabelle André-Schmutz,Marina Cavazzana-Calvo,Jean Claude Gluckman,Anne-Lise Delezoide,Françoise Pflumio,Bruno Canque +13 more
TL;DR: F fetal bone marrow (BM)-derived CD34hiCD45RAhiCD7+ hematopoietic progenitors are identified as thymus-colonizing cells that represent the direct precursors of the most immature CD34HICD1a- fetal thymocytes that follow a similar dynamics pattern during fetal and early postnatal development.