C
Camilla Simmons
Researcher at King's College London
Publications - 30
Citations - 517
Camilla Simmons is an academic researcher from King's College London. The author has contributed to research in topics: Biology & Hippocampus. The author has an hindex of 7, co-authored 21 publications receiving 333 citations. Previous affiliations of Camilla Simmons include Wellcome Trust.
Papers
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Proc. Intl. Soc. Mag. Reson. Med.
Robert Westphal,Camilla Simmons,Michel Mesquita,Tobias C. Wood,William R. Crum,Denise A Duricki,Anthony C. Vernon,Steven Williams,Diana Cash +8 more
Journal ArticleDOI
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice
Renzo Mancuso,Gemma L. Fryatt,Madeleine Cleal,Juliane Obst,Elena Pipi,Jimena Monzón-Sandoval,Jimena Monzón-Sandoval,Elena M. Ribe,Laura Winchester,Caleb Webber,Caleb Webber,Alejo J. Nevado,Tom Jacobs,Nigel Austin,Clara Theunis,Karolien Grauwen,Eva Daniela Ruiz,Amrit Mudher,Marta Vicente-Rodriguez,Christine A. Parker,Camilla Simmons,Diana Cash,Jill C. Richardson,Declan N.C. Jones,Simon Lovestone,Simon Lovestone,Diego Gomez-Nicola,V. Hugh Perry +27 more
TL;DR: Blockade of microglial proliferation by CSF1R inhibitor JNJ-40346527 modifies brain inflammation and ameliorates disease progression in P301S tauopathy mice, suggesting CSF 1R inhibition may have therapeutic potential in tau-mediated neurodegenerative diseases.
Journal ArticleDOI
Whole-brain ex-vivo quantitative MRI of the cuprizone mouse model.
Tobias C. Wood,Camilla Simmons,Samuel A. Hurley,Anthony C. Vernon,Joel Torres,Flavio Dell'Acqua,Steve C.R. Williams,Diana Cash +7 more
TL;DR: The whole brain of the cuprizone mouse ex-vivo is imaged and analyzed using high-resolution quantitative MR methods and changes in multiple regions are found, including the corpus callosum, cerebellum, thalamus and hippocampus.
Journal ArticleDOI
Sarm1 deletion suppresses TDP-43-linked motor neuron degeneration and cortical spine loss.
Matthew White,Ziqiang Lin,Ziqiang Lin,Eugene Kim,Christopher M. Henstridge,Emiliano Pena Altamira,Camille K. Hunt,Ella Burchill,Isobel Callaghan,Andrea Loreto,Heledd Brown-Wright,Richard J. Mead,Camilla Simmons,Diana Cash,Michael P. Coleman,Michael P. Coleman,Jemeen Sreedharan +16 more
TL;DR: Results indicate that anti-SARM1 strategies have therapeutic potential in ALS-FTD, and suggest a detrimental role of Wallerian-like pathways in the earliest stages of TDP-43Q331K-mediated neurodegeneration.
Journal ArticleDOI
Stroke Recovery in Rats after 24-Hour-Delayed Intramuscular Neurotrophin-3 Infusion.
Denise A Duricki,Denise A Duricki,Svetlana Drndarski,Michel Bernanos,Tobias C. Wood,Karen D. Bosch,Qin Chen,H. David Shine,Camilla Simmons,Steven Williams,Stephen B. McMahon,David J. Begley,Diana Cash,Lawrence D. F. Moon,Lawrence D. F. Moon +14 more
TL;DR: The hypothesis that intramuscular infusion of NT3 protein could improve sensorimotor recovery after stroke in adult and elderly rats is tested.