Can Hasdemir

TL;DR: Findings implicate SCN1B as a disease gene for human arrhythmia susceptibility, which encodes the function-modifying sodium channel beta1 subunit, in 282 probands with Brugada syndrome and in 44 patients with conduction disease, none of whom had SCN5A mutations.

TL;DR: The J-wave syndromes (JWSs) consisting of the Brugada syndrome (BrS) and early repolarization syndrome (ERS) have captured the interest of the cardiology community over the past 2 decades following the identification of BrS as a new clinical entity.

TL;DR: This study identified SCN10A as a major susceptibility gene for BrS, thus greatly enhancing the ability to genotype and risk stratify probands and family members.

TL;DR: This paper presents a meta-analyses of the determinants of infectious disease in eight operation theatres of the immune system using a model derived from previously published studies in the Journal of Adversarial and Pathology.

TL;DR: The results suggest that spontaneous AVNRT and concealed BrS co-occur, particularly in female patients, and that genetic variants that reduce sodium channel current may provide a mechanistic link between AVN RT and BrS and predispose to expression of both phenotypes.