C
Carla Petrella
Researcher at National Research Council
Publications - 84
Citations - 913
Carla Petrella is an academic researcher from National Research Council. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 14, co-authored 55 publications receiving 568 citations. Previous affiliations of Carla Petrella include Policlinico Umberto I & Sapienza University of Rome.
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Journal ArticleDOI
In vitro and in vivo pharmacological role of TLQP-21, a VGF-derived peptide, in the regulation of rat gastric motor functions
Cinzia Severini,G La Corte,Giovanna Improta,Maria Broccardo,Simona Agostini,Carla Petrella,Valeria Sibilia,Francesca Pagani,Francesca Guidobono,I. Bulgarelli,Gian-Luca Ferri,Carla Brancia,Anna Maria Rinaldi,Andrea Levi,Roberta Possenti +14 more
TL;DR: The effects of TLQP-21 were examined in vitro by smooth muscle contraction in isolated preparations from the rat gastrointestinal tract and, in vivo, by assessing gastric emptying in rats as discussed by the authors.
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Peripheral anti-nociceptive effect of nociceptin/orphanin FQ in inflammation and stress-induced colonic hyperalgesia in rats.
Simona Agostini,Simona Agostini,Helene Eutamene,Maria Broccardo,Giovanna Improta,Carla Petrella,V. Theodorou,Lionel Bueno +7 more
TL;DR: Findings indicate that in rats, N/OFQ, only peripherally injected, reduces visceral hypersensitivity triggered by inflammation or stress without affecting basal sensitivity.
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Pharmacological inhibition of 2-arachidonoilglycerol hydrolysis enhances memory consolidation in rats through CB2 receptor activation and mTOR signaling modulation.
Patrizia Ratano,Carla Petrella,Fabrizio Forti,Pamela Petrocchi Passeri,Maria Morena,Maura Palmery,Viviana Trezza,Cinzia Severini,Patrizia Campolongo +8 more
TL;DR: A fundamental role for 2‐AG and CB2 receptors in the modulation of memory consolidation for aversive experiences is identified andarmacological potentiation of 2‐ AG tone enhances memory consolidation through activation of CB2 receptor signaling.
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Evidence of central and peripheral sensitization in a rat model of narcotic bowel-like syndrome.
Simona Agostini,Simona Agostini,Helene Eutamene,Christel Cartier,Maria Broccardo,Giovanna Improta,Eric Houdeau,Carla Petrella,Laurent Ferrier,V. Theodorou,Lionel Bueno +10 more
TL;DR: A rat model of narcotic bowel-like syndrome was developed and showed that spinal microglia activation mediates the development of morphine-induced visceral hyperalgesia; peripheral neuroimmune activation and spinal dynorphin release represent an important mechanism in the delayed and long-lasting morphine- induced colonic hypersensitivity response to CRD.
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Oxidative stress inhibition by resveratrol in alcohol-dependent mice
Carla Petrella,Valentina Carito,Claudio Carere,Giampiero Ferraguti,Stefania Ciafrè,Fausta Natella,Cristiano Bello,Antonio Greco,Massimo Ralli,Rosanna Mancinelli,Marisa Patrizia Messina,Marco Fiore,Mauro Ceccanti +12 more
TL;DR: Prolonged consumption of resveratrol strongly counteracts serum radical oxygen species formation caused by chronic alcohol intake without effects on natural, free oxygen radical defense and can counteract alcohol-induced BDNF elevation in the liver, which is the main target of organ alcohol- induced damage.