C
Carlos Castillo-Henkel
Researcher at Instituto Politécnico Nacional
Publications - 24
Citations - 318
Carlos Castillo-Henkel is an academic researcher from Instituto Politécnico Nacional. The author has contributed to research in topics: Phenylephrine & Aorta. The author has an hindex of 11, co-authored 24 publications receiving 295 citations.
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Journal ArticleDOI
Bioassay-guided isolation of an anti-ulcer chromene from Eupatorium aschenbornianum: Role of nitric oxide, prostaglandins and sulfydryls
María Elena Sánchez-Mendoza,Benito Reyes-Trejo,Paula Sánchez-Gómez,Juan Rodríguez-Silverio,Carlos Castillo-Henkel,Humberto Cervantes-Cuevas,Jesús Arrieta +6 more
TL;DR: The results show that E. aschenbornianum had gastroProtective activity, that the hexane extract had the highest protective activity, and that encecanescin isolated from this extract was the main active gastroprotective agent.
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Synthesis and evaluation of the cardiovascular effects of two, membrane impermeant, macromolecular complexes of dextran-testosterone.
Lauro Figueroa-Valverde,Héctor Luna,Carlos Castillo-Henkel,Olga Muñoz-Garcı́a,Tomas Morato-Cartagena,Guillermo Ceballos-Reyes +5 more
TL;DR: Results showed that the macromolecular complexes increased vascular resistance similarly to free testosterone and blocked adenosine-induced vasodilatation and exerted rapidly and possibly through a non-genomic mechanism.
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Characterization of the potentiation of the antinociceptive effect of diclofenac by vitamin B complex in the rat
Gerardo Reyes-García,Roberto Medina-Santillán,Flavio Terán-Rosales,Eduardo Mateos-García,Carlos Castillo-Henkel +4 more
TL;DR: It is concluded that the potentiation of diclofenac-induced antinociception in the PIFIR model is due to cyanocobalamin.
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Kidney damage after renal ablation is worsened in endothelial nitric oxide synthase -/- mice and improved by combined administration of L-arginine and antioxidants.
Monica G. Arellano Mendoza,Carlos Castillo-Henkel,Roberto Medina-Santillán,R Adriana Jarillo Luna,Hilda Vargas Robles,Eunice Romo,Amelia Rios,Bruno Escalante +7 more
TL;DR: It is unclear whether NO prevents or acts as the compound responsible for the cytotoxicity observed during kidney failure, and stimulation of the NO pathway ameliorates the progression of kidney failure.
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Bioassay-guided isolation of an anti-ulcer diterpenoid from Croton reflexifolius : role of nitric oxide, prostaglandins and sulfhydryls
Benito Reyes-Trejo,María Elena Sánchez-Mendoza,Anabel Ariana Becerra-García,Ernestina Cedillo-Portugal,Carlos Castillo-Henkel,Jesús Arrieta +5 more
TL;DR: Polyalthic acid, which was isolated from this plant, was the main compound with gastroprotector activity, having effectiveness similar to that found with the use of carbenoxolone.