Journal ArticleDOI
Bioassay-guided isolation of an anti-ulcer chromene from Eupatorium aschenbornianum: Role of nitric oxide, prostaglandins and sulfydryls
María Elena Sánchez-Mendoza,Benito Reyes-Trejo,Paula Sánchez-Gómez,Juan Rodríguez-Silverio,Carlos Castillo-Henkel,Humberto Cervantes-Cuevas,Jesús Arrieta +6 more
TLDR
The results show that E. aschenbornianum had gastroProtective activity, that the hexane extract had the highest protective activity, and that encecanescin isolated from this extract was the main active gastroprotective agent.About:
This article is published in Fitoterapia.The article was published on 2010-01-01. It has received 38 citations till now.read more
Citations
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Journal ArticleDOI
Antisecretory, Gastroprotective, Antioxidant and Anti-Helicobcter Pylori Activity of Zerumbone from Zingiber Zerumbet (L.) Smith
Heyam Mohamed Ali Sidahmed,Najihah Mohd Hashim,Mahmood Ameen Abdulla,Hapipah Mohd Ali,Syam Mohan,Siddig Ibrahim Abdelwahab,Manal Mohamed Elhassan Taha,Loke Mun Fai,Jamuna Vadivelu +8 more
TL;DR: It is revealed that zerumbone promotes ulcer protection, which might be attributed to the maintenance of mucus integrity, antioxidant activity, and HSP-70 induction.
Journal ArticleDOI
Gastroprotective Effect of Zingerone on Ethanol-Induced Gastric Ulcers in Rats.
TL;DR: The present study showed that zingerone has a protective effect on the ethanol-induced gastric ulcer, which may be due to its free radical scavenging activity.
Journal ArticleDOI
Chemical Constituents of Plants from the Genus Eupatorium (1904-2014).
Pei-Yu Liu,Dan Liu,Wei-Huan Li,Ting Zhao,Francoise Sauriol,Yu-Cheng Gu,Yu-Cheng Gu,Qing-Wen Shi,Manli Zhang +8 more
TL;DR: More than 300 monomeric compounds or active parts have been screened for pharmacological activities from Eupatorium in vivo and in vitro, and increasing amount of data supports application and exploitation for new drug development.
Journal ArticleDOI
Bioassay-guided isolation of an anti-ulcer compound, tagitinin C, from Tithonia diversifolia: Role of nitric oxide, prostaglandins and sulfhydryls
María Elena Sánchez-Mendoza,Adelfo Reyes-Ramírez,Leticia Cruz Antonio,Luis Martínez Jiménez,Juan Rodríguez-Silverio,Jesús Arrieta +5 more
TL;DR: The results showed that T. diversifolia had gastroprotective activity, and that the dichloromethane extract had the highest protective activity (close to 90% when using doses between 10 to 100 mg/kg), and that further the compound tagitinin C isolated from this extract was the main active gastroprot protective agent.
Journal ArticleDOI
Effectiveness of Opuntia ficus indica L. inermis Seed Oil in the Protection and the Healing of Experimentally Induced Gastric Mucosa Ulcer
Ikram Khemiri,Lotfi Bitri +1 more
TL;DR: In this article, the preventive and curative effects of OFI seed oil extracted by cold pressing on an ethanol-induced gastric ulcer model in rats were investigated, and the authors found that OFI oil exhibited a high efficiency in the protection of the cytoarchitecture and function of the gastric mucosa against severe damages provoked by ethanol intake.
References
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Journal ArticleDOI
Cytoprotection by prostaglandins.
TL;DR: A new property of PG was discovered, called "cytoprotection,"!' which designates the prop- erty of many PG to protect the mucosa of the stom- ach and the intestine from becoming inflamed and necrotic, when this mucosa is exposed to noxious agents.
Journal ArticleDOI
The plant kingdom as a source of anti‐ulcer remedies
TL;DR: Despite progress in conventional chemistry and pharmacology in producing effective drugs, the plant kingdom might provide a useful source of new anti‐ulcer compounds for development as pharmaceutical entities or as simple dietary adjuncts to existing therapies.
Journal ArticleDOI
Anti-gastric ulcer effect of Kaempferia parviflora.
TL;DR: The findings indicate that the ethanolic extract of Kaempferia parviflora possesses gastroprotective potential which is related partly to preserved gastric mucus secretion and unrelated to the inhibition of gastric acid secretion.
Journal ArticleDOI
Roles of capsaicin-sensitive sensory nerves, endogenous nitric oxide, sulfhydryls, and prostaglandins in gastroprotection by momordin Ic, an oleanolic acid oligoglycoside, on ethanol-induced gastric mucosal lesions in rats
TL;DR: It is suggested that CPSN play an important role in the gastroprotection by momordin Ic on ethanol-induced gastric mucosal lesions, and endogenous PGs, NO, and SHs interactively participate, in rats.
Journal ArticleDOI
Purification of gastroprotective triterpenoids from the stem bark of Amphipterygium adstringens; role of prostaglandins, sulfhydryls, nitric oxide and capsaicin-sensitive neurons.
TL;DR: The results suggest that endogenous nitric oxide plays an important role in the gastroprotection of A. adstringens methanol extract on ethanol-induced gastric mucosal lesions and that there is partial participation by prostaglandins and endogenous sulfhydryls.