Journal ArticleDOI
Synthesis and evaluation of the cardiovascular effects of two, membrane impermeant, macromolecular complexes of dextran-testosterone.
Lauro Figueroa-Valverde,Héctor Luna,Carlos Castillo-Henkel,Olga Muñoz-Garcı́a,Tomas Morato-Cartagena,Guillermo Ceballos-Reyes +5 more
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TLDR
Results showed that the macromolecular complexes increased vascular resistance similarly to free testosterone and blocked adenosine-induced vasodilatation and exerted rapidly and possibly through a non-genomic mechanism.About:
This article is published in Steroids.The article was published on 2002-06-01. It has received 37 citations till now. The article focuses on the topics: Mechanism of action.read more
Citations
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Androgens and cardiovascular disease.
TL;DR: The commonality of risk factor patterns and mechanisms suggests that the efficacy of antiatherogenic therapy is an important challenge with the potential to enhance men's motivation for prevention and treatment of cardiovascular diseases.
Journal ArticleDOI
Introduction to the practice of statistics, (3rd edition), by David S. Moore and George P. McCabe. Pp. 825 (with appendices and CD-ROM). £27.95. 1999. ISBN 0 7167 3502 4 (W. H. Freeman).
Journal ArticleDOI
Non-genomic Actions of Androgens
TL;DR: The non-genomic effects of androgens are reviewed, along with a discussion of the possible role non- genomic androgen actions have on animal physiology and behavior.
Journal ArticleDOI
Non-genomic actions of sex steroid hormones
TL;DR: The evidence collected in the past Years indicates that target cells and organs are regulated by a complex interplay of genomic and non-genomic signaling mechanisms of steroid hormones, and the integrated action of these machineries has important functional roles in a variety of pathophysiological processes.
Journal ArticleDOI
Receptor mechanisms mediating non-genomic actions of sex steroids.
TL;DR: Recent advances in the understanding of the nature of the receptors and mechanisms responsible for rapid non-genomic signaling actions of sex steroids, including novel membrane receptors and interactions of nuclear steroid receptors with membrane and cytoplasmic signaling molecules such as adapter proteins, G proteins, ion channels, and protein kinases are focused on.
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Journal ArticleDOI
Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the nurses' health study.
Meir J. Stampfer,Graham A. Colditz,Walter C. Willett,JoAnn E. Manson,Bernard Rosner,Frank E. Speizer,Charles H. Hennekens +6 more
TL;DR: Current estrogen use is associated with a reduction in the incidence of coronary heart disease as well as in mortality from cardiovascular disease, but it is not associated with any change in the risk of stroke.
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Steroid-protein conjugates. I. Preparation and characterization of conjugates of bovine serum albumin with testosterone and with cortisone.
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Non-genomic and genomic effects of steroids on neural activity
TL;DR: Evidence that synergistic interactions occur between non-genomic and genomic actions of steroids is reviewed, showing that progesterone appears to be one of the most active of the steroids, and its naturally produced metabolites and some synthetic analogs show activities that are different from the parent steroid.
Journal ArticleDOI
Postmenopausal estrogen therapy and cardiovascular disease.
D B MacLean,Andrew G. Bostom +1 more
TL;DR: In this article, the effect of postmenopausal estrogen therapy on the risk of cardiovascular disease remains controversial, and the authors used the Nurses' Health Study (NHS) with 48,470 participants to study the effects of estrogen therapy.