C
Carly Langan
Researcher at Broad Institute
Publications - 2
Citations - 20
Carly Langan is an academic researcher from Broad Institute. The author has contributed to research in topics: Profiling (computer programming) & Generalizability theory. The author has an hindex of 1, co-authored 1 publications receiving 3 citations.
Papers
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Posted ContentDOI
Phosphate dysregulation via the XPR1:KIDINS220 protein complex is a therapeutic vulnerability in ovarian cancer
Daniel P. Bondeson,Brenton R. Paolella,Adhana Asfaw,Michael V. Rothberg,Thomas A. Skipper,Carly Langan,Alfredo Gonzalez,Lauren E. Surface,Kentaro Ito,Mariya Kazachkova,William Colgan,Allison Warren,Josh Dempster,Mike Burger,Maria Ericsson,Andrew Tang,Iris Fung,Emily Chambers,Mai Abdusamad,Nancy Dumont,John G. Doench,Federica Piccioni,David E. Root,Jesse S. Boehm,William C. Hahn,William C. Hahn,Michael Mannstadt,James M. McFarland,Francisca Vazquez,Todd R. Golub,Todd R. Golub +30 more
TL;DR: All data point to the XPR1:KIDINS220 complex - and phosphate dysregulation more broadly - as a therapeutic vulnerability in ovarian cancer.
Journal ArticleDOI
Systematic profiling of conditional degron tag technologies for target validation studies
Daniel Bondeson,Zachary Mullin-Bernstein,Sydney Oliver,Thomas A. Skipper,Thomas C. Atack,Meilani Ching,Andrew A Guirguis,Jason J. Kwon,Carly Langan,Dylan Millson,Brenton R. Paolella,Kevin Tran,Sarah J. Wie,Francisca Vazquez,Zuzana Tothova,Todd R. Golub,William R. Sellers,Alessandra Ianari +17 more
TL;DR: In this paper , the authors report a system to rapidly compare the activity of five unique CDTs: AID/AID2, IKZF3d, dTAG, HaloTag, and SMASh.