C
Carmine Gentile
Researcher at University of Technology, Sydney
Publications - 47
Citations - 2040
Carmine Gentile is an academic researcher from University of Technology, Sydney. The author has contributed to research in topics: Medicine & Stem cell. The author has an hindex of 15, co-authored 38 publications receiving 1654 citations. Previous affiliations of Carmine Gentile include Sewanee: The University of the South & Harvard University.
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Organ Printing: Tissue Spheroids as Building Blocks
Vladimir Mironov,Jing Zhang,Carmine Gentile,K Brakke,Thomas C. Trusk,Karoly Jakab,Gabor Forgacs,Vladimirs Kasjanovs,Richard P. Visconti,Roger R. Markwald +9 more
TL;DR: Organ printing can be defined as layer-by-layer additive robotic biofabrication of three-dimensional functional living macrotissues and organ constructs using tissue spheroids as building blocks.
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Towards organ printing: engineering an intra-organ branched vascular tree
Richard P. Visconti,Vladimir Kasyanov,Carmine Gentile,Jing Zhang,Roger R. Markwald,Vladimir Mironov +5 more
TL;DR: This work presents the emerging concept of organ printing or robotic additive biofabrication of an intra-organ branched vascular tree, based on the ability of vascular tissue spheroids to undergo self-assembly for tissue engineering based on organ-printing technology using self-assembling vascular tissue Spheroids.
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Cardiac spheroids as promising in vitro models to study the human heart microenvironment.
Liudmila Polonchuk,Mamta Chabria,Laura Badi,Jean-Christophe Hoflack,Gemma A. Figtree,Michael J. Davies,Carmine Gentile,Carmine Gentile,Carmine Gentile +8 more
TL;DR: Three-dimensional in vitro models of the human heart are generated by co-culturing human primary or iPSC-derived cardiomyocytes, endothelial cells and fibroblasts at ratios approximating those present in vivo, indicating that CSs mimic important features of human heart morphology, biochemistry and pharmacology in vitro.
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Fusion of uniluminal vascular spheroids: a model for assembly of blood vessels
Paul A. Fleming,W. Scott Argraves,Carmine Gentile,Adrian Neagu,Gabor Forgacs,Christopher J. Drake +5 more
TL;DR: The findings indicate that tissue liquidity underlies uniluminal vascular spheroid fusion and that in vivo anastomosis of blood vessels may involve a similar mechanism.
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Glutathionylation mediates angiotensin II-induced eNOS uncoupling, amplifying NADPH oxidase-dependent endothelial dysfunction.
Keyvan Karimi Galougahi,Chia‐Chi-C. Liu,Carmine Gentile,Carmine Gentile,Cindy Kok,Andrea C. Nunez,Alvaro Garcia,N. Fry,Michael J. Davies,Michael J. Davies,Clare L. Hawkins,Clare L. Hawkins,Helge H. Rasmussen,Helge H. Rasmussen,Gemma A. Figtree,Gemma A. Figtree +15 more
TL;DR: It is suggested that Ang II‐induced O2•− generation in endothelial cells, although dependent on NADPH oxidase, is amplified by glutathionylation‐dependent eNOS uncoupling.