C
Carol A. Wallace
Researcher at Seattle Children's
Publications - 23
Citations - 974
Carol A. Wallace is an academic researcher from Seattle Children's. The author has contributed to research in topics: Vasculitis & Data warehouse. The author has an hindex of 15, co-authored 23 publications receiving 838 citations. Previous affiliations of Carol A. Wallace include University at Buffalo.
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Journal ArticleDOI
2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis
Angelo Ravelli,Francesca Minoia,Sergio Davì,AnnaCarin Horne,Francesca Bovis,Angela Pistorio,Maurizio Aricò,Tadej Avcin,Edward M. Behrens,Fabrizio De Benedetti,Lisa Filipovic,Alexei A. Grom,Jan-Inge Henter,Norman T. Ilowite,Michael B. Jordan,Raju Khubchandani,Toshiyuki Kitoh,Kai Lehmberg,Daniel J. Lovell,Paivi Miettunen,Kim E. Nichols,Seza Ozen,Jana Pachlopnik Schmid,Athimalaipet V Ramanan,Ricardo Russo,Rayfel Schneider,Gary Sterba,Yosef Uziel,Carol A. Wallace,Carine Wouters,Nico M Wulffraat,Erkan Demirkaya,Hermine I. Brunner,Alberto Martini,Nicolino Ruperto,Randy Q. Cron +35 more
TL;DR: A set of classification criteria for MAS complicating systemic JIA is developed and preliminary evidence of its validity is provided, which will potentially improve understanding of MAS in systemic Jia and enhance efforts to discover effective therapies, by ensuring appropriate patient enrollment in studies.
Journal ArticleDOI
Disease activity assessment in childhood vasculitis: development and preliminary validation of the Paediatric Vasculitis Activity Score (PVAS)
Pavla Dolezalova,Fiona E Price-Kuehne,Seza Ozen,Susanne M. Benseler,David A. Cabral,Jordi Anton,Jürgen Brunner,Rolando Cimaz,Katheleen M O'Neil,Carol A. Wallace,Nick Wilkinson,Despina Eleftheriou,Erkan Demirkaya,Marek Böhm,Petra Król,Raashid Luqmani,Paul A. Brogan +16 more
TL;DR: The PVAS validity in children with systemic vasculitis was demonstrated and it is anticipated that the PVAS will provide a robust tool to objectively define disease activity for clinical trials and future research.
Journal ArticleDOI
A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment
Roberto Spreafico,Maura Rossetti,Jorg van Loosdregt,Carol A. Wallace,Margherita Massa,Silvia Magni-Manzoni,Marco Gattorno,Alberto Martini,Daniel J. Lovell,Salvatore Albani +9 more
TL;DR: CPLs provide an accessible reservoir of pathogenic cells recirculating into the bloodstream and correlating with disease activity, to be exploited for diagnostic and research purposes.
Journal ArticleDOI
An i2b2-based, generalizable, open source, self-scaling chronic disease registry
Marc D. Natter,Justin Quan,David M. Ortiz,Athos Bousvaros,Norman T. Ilowite,Christi J. Inman,Keith Marsolo,Andrew J. McMurry,Christy Sandborg,Laura E. Schanberg,Carol A. Wallace,Robert W. Warren,Griffin M. Weber,Kenneth D. Mandl,Kenneth D. Mandl +14 more
TL;DR: In this paper, the authors design a self-scaling registry technology for collaborative data sharing, based upon the widely adopted Integrating Biology & the Bedside (i2b2) data warehousing framework and the Shared Health Research Information Network (SHRINE) peer-to-peer networking software.
Journal Article
An i2b2-based, generalizable, open source, self-scaling chronic disease registry
Marc D. Natter,Justin Quan,David M. Ortiz,Athos Bousvaros,Norman T. Ilowite,Christi J. Inman,Keith Marsolo,Andrew J. McMurry,Christy Sandborg,Laura E. Schanberg,Carol A. Wallace,Robert W. Warren,Griffin M. Weber,Kenneth D. Mandl,Kenneth D. Mandl +14 more
TL;DR: The implementation of i2b2-SSR for the multi-site, multi-stakeholder CARRA Registry has established a digital infrastructure for community-driven research data sharing in pediatric rheumatology in the USA.