C
Carol Chapman
Researcher at Naval Medical Research Center
Publications - 7
Citations - 157
Carol Chapman is an academic researcher from Naval Medical Research Center. The author has contributed to research in topics: Genome & Vibrio cholerae. The author has an hindex of 7, co-authored 7 publications receiving 132 citations.
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Journal ArticleDOI
Genomic Signatures of Strain Selection and Enhancement in Bacillus atrophaeus var. globigii, a Historical Biowarfare Simulant
Henry S. Gibbons,S. M. Broomall,Lauren A. McNew,Lauren A. McNew,Hajnalka E. Daligault,Carol Chapman,David Bruce,Mark Karavis,Michael D. Krepps,Paul McGregor,Paul McGregor,Charles Hong,Charles Hong,Kyong H. Park,Arya Akmal,Andrew B. Feldman,Jeffrey S. Lin,Wenling E. Chang,Brandon W. Higgs,Plamen A. Demirev,John Lindquist,Alvin T. Liem,Ed Fochler,Timothy D. Read,Roxanne Tapia,Shannon L. Johnson,Kimberly A. Bishop-Lilly,Chris Detter,Cliff Han,Shanmuga Sozhamannan,C. Nicole Rosenzweig,Evan W. Skowronski +31 more
TL;DR: The power of whole-genome and modern systems-level approaches to characterize microbial lineages to develop and validate forensic markers for strain discrimination and reveal signatures of deliberate adaptation is demonstrated.
Journal ArticleDOI
Whole genome sequencing of phage resistant Bacillus anthracis mutants reveals an essential role for cell surface anchoring protein CsaB in phage AP50c adsorption.
Kimberly A. Bishop-Lilly,Roger D. Plaut,Peter E. Chen,Arya Akmal,Kristin M Willner,Amy Butani,Shakia Dorsey,Vishwesh P. Mokashi,Alfred J. Mateczun,Carol Chapman,Matroner George,Truong Luu,Timothy D. Read,Richard Calendar,Scott Stibitz,Shanmuga Sozhamannan +15 more
TL;DR: The whole genome sequences generated from this study suggest an essential role for csaB in AP50c phage infection, most likely in phage adsorption.
Journal ArticleDOI
Comprehensive Laboratory Evaluation of a Highly Specific Lateral Flow Assay for the Presumptive Identification of Bacillus anthracis Spores in Suspicious White Powders and Environmental Samples
Jason G Ramage,Kristin W. Prentice,Lindsay DePalma,Kodumudi S. Venkateswaran,Sruti Chivukula,Carol Chapman,Melissa Bell,Shomik Datta,Ajay Singh,Alex R. Hoffmaster,Jawad Sarwar,Nishanth Parameswaran,Mrinmayi Joshi,Nagarajan Thirunavkkarasu,Viswanathan V Krishnan,Stephen Morse,Julie R. Avila,Shashi Sharma,Peter L. Estacio,Larry H. Stanker,David R. Hodge,Segaran P. Pillai +21 more
TL;DR: The results indicated that the specificity, sensitivity, limit of detection, dynamic range, and repeatability of the assay support its use in the field for the purpose of qualitatively evaluating suspicious white powders and environmental samples for the presumptive presence of B. anthracis spores.
Journal ArticleDOI
Scanning the landscape of genome architecture of non-O1 and non-O139 Vibrio cholerae by whole genome mapping reveals extensive population genetic diversity.
Carol Chapman,Matthew Henry,Kimberly A. Bishop-Lilly,Joy Awosika,Adam Briska,Ryan Ptashkin,Trevor K. Wagner,Chythanya Rajanna,Hsinyi Tsang,Shannon L. Johnson,Vishwesh P. Mokashi,Patrick S. G. Chain,Shanmuga Sozhamannan +12 more
TL;DR: The Whole Genome Mapping approach presented here enables rapid screening of large strain collections to capture genomic complexities that would not have been otherwise revealed by unfinished draft genome sequencing and thus aids in assembling and finishing draft sequences of complex genomes.
Journal ArticleDOI
Complete genome assemblies for two single-chromosome Vibrio cholerae isolates, strains 1154-74 (serogroup O49) and 10432-62 (serogroup O27)
Shannon L. Johnson,A. Khiani,Kimberly A. Bishop-Lilly,Carol Chapman,M. Patel,Kathleen Verratti,Hazuki Teshima,A. C. Munk,David Bruce,Cliff Han,Gary Xie,Karen W. Davenport,Patrick S. G. Chain,Shanmuga Sozhamannan +13 more
TL;DR: The completed genome sequences for two non-O1/non-O139 Vibrio cholerae isolates are reported, each isolate has only a single chromosome, as opposed to the normal paradigm of two chromosomes found in all other V. cholerance isolates.