R
Roxanne Tapia
Researcher at Los Alamos National Laboratory
Publications - 153
Citations - 5492
Roxanne Tapia is an academic researcher from Los Alamos National Laboratory. The author has contributed to research in topics: Genome & Whole genome sequencing. The author has an hindex of 34, co-authored 153 publications receiving 4971 citations. Previous affiliations of Roxanne Tapia include University of California, Davis & Joint Genome Institute.
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Journal ArticleDOI
Three Genomes from the Phylum Acidobacteria Provide Insight into the Lifestyles of These Microorganisms in Soils
Naomi L. Ward,Jean F. Challacombe,Jean F. Challacombe,Peter H. Janssen,Peter H. Janssen,Bernard Henrissat,Pedro M. Coutinho,Martin Wu,Gary Xie,Gary Xie,Daniel H. Haft,Michelle Sait,Jonathan H. Badger,Ravi D. Barabote,Ravi D. Barabote,Brent Bradley,Thomas Brettin,Thomas Brettin,Lauren M. Brinkac,David Bruce,David Bruce,Todd Creasy,Sean C. Daugherty,Tanja M. Davidsen,Robert T. DeBoy,J. Chris Detter,J. Chris Detter,Robert J. Dodson,A. Scott Durkin,Anuradha Ganapathy,Michelle Gwinn-Giglio,Cliff Han,Cliff Han,Hoda Khouri,Hajnalka Kiss,Hajnalka Kiss,Sagar Kothari,Ramana Madupu,Karen E. Nelson,William C. Nelson,Ian T. Paulsen,Kevin Penn,Qinghu Ren,M. J. Rosovitz,Jeremy D. Selengut,Susmita Shrivastava,Steven A. Sullivan,Roxanne Tapia,Roxanne Tapia,L. Sue Thompson,L. Sue Thompson,Kisha Watkins,Qi Yang,Chunhui Yu,Nikhat Zafar,Liwei Zhou,Cheryl R. Kuske +56 more
TL;DR: Combining the genomic evidence with available culture traits, it is postulate that cells of these isolates are long-lived, divide slowly, exhibit slow metabolic rates under low-nutrient conditions, and are well equipped to tolerate fluctuations in soil hydration.
Journal ArticleDOI
Pathogenomic Sequence Analysis of Bacillus cereus and Bacillus thuringiensis Isolates Closely Related to Bacillus anthracis
Cliff Han,Gary Xie,Jean F. Challacombe,Michael R. Altherr,Smriti S. Bhotika,David Bruce,Connie S. Campbell,Mary L. Campbell,Jin Chen,Olga Chertkov,Cathy Cleland,Mira Dimitrijevic,Norman A. Doggett,John J. Fawcett,Tijana Glavina,Tijana Glavina,Lynne Goodwin,Karen K. Hill,Penny Hitchcock,Paul J. Jackson,Paul J. Jackson,Paul Keim,Avinash Ramesh Kewalramani,Jon Longmire,Susan Lucas,Susan Lucas,Stephanie Malfatti,Stephanie Malfatti,Kim McMurry,Linda Meincke,Monica Misra,Bernice L. Moseman,Mark Mundt,A. Christine Munk,Richard T. Okinaka,B. Parson-Quintana,Lee Philip Reilly,Paul Richardson,Paul Richardson,Donna L. Robinson,Eddy Rubin,Eddy Rubin,Elizabeth Saunders,Roxanne Tapia,Judith G. Tesmer,Nina Thayer,Linda S. Thompson,Hope Tice,Hope Tice,Lawrence O. Ticknor,Patti L. Wills,Thomas Brettin,Paul Gilna +52 more
TL;DR: Comparison of the genomes of two members of the B. cereus group revealed differences in terms of virulence, metabolic competence, structural components, and regulatory mechanisms, as well as shared and unique genes among these isolates in comparison to the genome of pathogenic strains B. anthracis Ames and B. cerealus.
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Genome sequence of the cellulolytic gliding bacterium Cytophaga hutchinsonii.
Gary Xie,Gary Xie,David Bruce,David Bruce,Jean F. Challacombe,Jean F. Challacombe,Olga Chertkov,Olga Chertkov,John C. Detter,John C. Detter,Paul Gilna,Paul Gilna,Cliff Han,Cliff Han,Susan Lucas,Susan Lucas,Monica Misra,Gerald Myers,Paul Richardson,Paul Richardson,Roxanne Tapia,Roxanne Tapia,Nina Thayer,Linda S. Thompson,Linda S. Thompson,Thomas Brettin,Thomas Brettin,Bernard Henrissat,David Wilson,Mark J. McBride +29 more
TL;DR: The complete DNA sequence of the aerobic cellulolytic soil bacterium Cytophaga hutchinsonii, which belongs to the phylum Bacteroidetes, is presented and many genes thought to encode proteins involved in cellulose utilization were identified.
Journal ArticleDOI
Temperature regulation of virulence factors in the pathogen Vibrio coralliilyticus
Nikole E. Kimes,Christopher J. Grim,Christopher J. Grim,Wesley R. Johnson,Nur A. Hasan,Ben D. Tall,Mahendra H. Kothary,Hajnalka Kiss,A. Christine Munk,Roxanne Tapia,Lance D. Green,Chris Detter,David Bruce,Thomas Brettin,Thomas Brettin,Rita R. Colwell,Rita R. Colwell,Pamela J. Morris +17 more
TL;DR: Evidence is provided that temperature regulates multiple virulence mechanisms in V. coralliilyticus, independent of abundance, which is reinforced by climate change models that predict tropical SST to consistently exceed 27 °C during the spring, summer and fall seasons.
Journal ArticleDOI
The Methanosarcina barkeri Genome: Comparative Analysis with Methanosarcina acetivorans and Methanosarcina mazei Reveals Extensive Rearrangement within Methanosarcinal Genomes
Dennis L. Maeder,Iain Anderson,Thomas Brettin,David Bruce,Paul Gilna,Cliff Han,Alla Lapidus,William W. Metcalf,Elizabeth Saunders,Roxanne Tapia,Kevin R. Sowers +10 more
TL;DR: A three-way comparison of these genomes reveals differing mechanisms for the accrual of changes, and the short M. mazei genome most closely approximates the putative ancestral organizational state of these species.