C
Carola Schubert
Researcher at Charité
Publications - 25
Citations - 2115
Carola Schubert is an academic researcher from Charité. The author has contributed to research in topics: Pressure overload & Muscle hypertrophy. The author has an hindex of 20, co-authored 25 publications receiving 1954 citations. Previous affiliations of Carola Schubert include Martin Luther University of Halle-Wittenberg.
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Journal ArticleDOI
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis.
Alexey Kotlyarov,Armin Neininger,Carola Schubert,Rolf Eckert,Carmen Birchmeier,Hans-Dieter Volk,Matthias Gaestel +6 more
TL;DR: It is concluded that MK2 is an essential component in the inflammatory response which regulates biosynthesis of TNF-α at a post-transcriptional level.
Journal ArticleDOI
Female sex and estrogen receptor-β attenuate cardiac remodeling and apoptosis in pressure overload
Daniela Fliegner,Carola Schubert,A. Penkalla,Henning Witt,Georgios Kararigas,Elke Dworatzek,Eike Staub,Peter Martus,Patricia Ruiz Noppinger,Ulrich Kintscher,Jan-Åke Gustafsson,Vera Regitz-Zagrosek +11 more
TL;DR: Both female sex and ERbeta attenuate the development of fibrosis and apoptosis, thus slowing the progression to heart failure, and the number of apoptotic nuclei was increased in both sexes of ERbeta(-/-)/TAC mice, most prominent in males.
Journal ArticleDOI
Regression of Myocardial Hypertrophy After Aortic Valve Replacement: Faster in Women?
George Petrov,Vera Regitz-Zagrosek,Elke Lehmkuhl,Thomas Krabatsch,Anne Dunkel,Michael Dandel,Elke Dworatzek,Shokoufeh Mahmoodzadeh,Carola Schubert,Eva Becher,Hannah Hampl,Roland Hetzer +11 more
TL;DR: In this article, the effect of 17β-estradiol on collagen synthesis in isolated rat cardiac fibroblasts was investigated in patients with isolated aortic stenosis.
Kotlyarov, A. et al. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat. Cell Biol. 1, 94-97
Alexey Kotlyarov,Armin Neininger,Carola Schubert,Rolf Eckert,Carmen Birchmeier,H. D. and Volk,Matthias Gaestel +6 more
Journal ArticleDOI
Sex-specific pathways in early cardiac response to pressure overload in mice
Henning Witt,Henning Witt,Carola Schubert,Juliane Jaekel,Daniela Fliegner,A. Penkalla,Klaus Tiemann,Joerg Stypmann,Stefan Roepcke,Sebastian Brokat,Shokoufeh Mahmoodzadeh,Eva Brozová,Mercy M. Davidson,Patricia Ruiz Noppinger,Patricia Ruiz Noppinger,Christian Grohé,Vera Regitz-Zagrosek +16 more
TL;DR: Female-specific genes related to mitochondria and metabolism and males to matrix and biosynthesis characterize the sex-specific early response to PO, which could contribute to subsequent sex differences in cardiac function and HF.